Androderm® system

The same technology has been utilized in the development of the following 1) the Estraderm system, which administers a controlled dose of estradiol transdermally over 3 days for the relief of postmenopausal syndrome and osteoporosis 2) the Duragesic system, which provides a transdermal-controlled administration of fentanyl, a potent narcotic analgesic, for 72-h relief of chronic pain and 3) the Androderm system, which provides a transdermal-controlled delivery of... 

Androderm, anotiier transdermal system, is applied nightly to clean, dry skin on the abdomen, tiiigh, back, or upper arm. This system is not applied to die scrotum. Sites are rotated, witii 7 days between application to any specific site The system is applied immediately after opening the pouch and removing die protective covering. If the patient has not exhibited a therapeutic response after 8 weeks of tiierapy, another form of testosterone replacement therapy should be considered. 

Androderm - The usual starting dose is one 5 mg system or two 2.5 mg systems applied nightly for 24 hours, providing a total dose of 5 mg/day. 

Androderm - Following application to nonscrotal skin, testosterone is continuously absorbed during the 24-hour dosing period. Daily application of 2 systems at approximately 10 00 p.m. results in a serum testosterone concentration profile that mimics the normal circadian variation observed in healthy young men. Maximum concentrations occur in the early morning hours with minimum concentrations in the evening. 

Parenteral 200 mg/mL for IM injection Testosterone transdermal system Patch (Androderm) 2.5, 5 mg/24 h release rate Gel (AndroGel) 1%... 

Bhasin S, Storer TW, Asbel-Sethi N, Kilbourne A, Hays R, Sinha-Hikim I, Shen R, Arver S, Beall G. Effects of testosterone replacement with a nongenital, transdermal system, Androderm, in human immunodeficiency virus-infected men with low testosterone levels. J Clin Endocrinol Metab 1998 83(9) 3155-62. 

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