Analyzer scanning speed

The usability of the calibration depends on the type of instrument and can last for a period of up to several days or weeks. All tuning parameters, in particular the adjustment of the ion source, affect the calibration as described above. In particular the analyzer scan speed has a strong impact on the mass calibration with many instruments. Special attention should also be paid to a constant temperature of the ion source. Regular mass calibration using analysis conditions is recommended to comply with the lab internal QA/QC (quality assurance/quality control) procedures. 

Physical properties of the prepared catalysts were measured by an adsorption analyzer [Quantachrome Co., Autosorb-lC]. The structure of prepared catalysts were investigated by XRD [Simmazdu Co., XRD-6000] with a Cu-Ka radiation source (X = 1.54056 A), voltage of 40.0 kV, ciurent of 30.0 mA and scan speed of 5.0 deg/min. Also, temperature-programmed reduction (TPR) profiles of the samples were investigated by a sorption analyzer [Micromeritics Co., Autochem II] and obtained by heating the samples from room temperature to 1100°C at a rate of lOTl/min in a 5 % H2/Ar gas flow (50 ml/min). 

The choice of an analyzer depends on the kind of studies and applications that will be carried out m/z range, resolution, mass accuracy, scan speed, number of mass separations, are some of the parameters that have to be considered. 

The speed of the analyzer highly depends on the mode of operation. The scan speed affects both the resolution and the mass accuracy, so if high quality data is needed, a... 

Due to the limited dynamic range the QIT is not a particularly good analyzer for quantification. For pure samples the problem is less pronounced, but if a background is present the background ions will constitute a substantial portion of the total number of ions entering the QIT and, hence, affect the quality of the quantification. Typical scan speeds arc 5 kTh/s (several commercial systems offer the possibility of different scan speeds). Higher resolution is attained by reducing the scan speed. 

In terms of overall sensitivity (one molecule detection), mass resolution (in excess of 10 ), mass accuracy (<2ppm), scan speed, and MS capabilities, PT-ICR analyzers remain a very promising technique for the on-line coupling with CE. However, its technical demands, in terms of vacuum technology, and its high price currently limits its use mostly to fundamental studies. 

To ensure they are clean, scan a rack containing ten Chromarod Sills on an Iatroscan TLC-FID analyzer using a scanning speed of 4 mm/sec, air flow of 2000 ml/min, and hydrogen flow of 160 ml/min. Scan once more if peaks can be seen in the first scan. 

The fast scanning speed (4000 amu/s), rapid cycle hme, and high sensitivity afforded by the AB/MDS Sciex QTrap allow the use of combined scan func-hons, such as precursor or neutral-loss MS/MS scans followed by product-ion MS/MS scans. Therefore, the hybrid triple-quadrupole/LIT could be the ideal platform for acquiring more useful informahon from every drug-metabolism sample currently analyzed by LC-MS/MS. 

Along with advances in various ionization sources, significant improvements have been made in the area of mass analyzers. Mass analyzers can be differentiated based on several attributes such as scan speed, duty cycle, mass resolution, mass range, and cost [126], The most common analyzers used for metabonomics analyses include the quadrupole and TOF-based analyzers [125-127], Some other analyzers that have been reported for use in MS-based metabonomics analyses are the ion traps, Orbitraps, and Fourier transform mass spectrometers [128,129],... 

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