Computer-aided data analysis

The methods used include operating experience and event data, geotectonic historical records, coupled neutronic-thermal-hydraulic transient performance analysis codes. Computer Aided Design-Computer Aided Engineering (CAD-CAE) systems, structural finite element methods, materials stress analysis. Human Reliability Analysis, risk assessments and PRAs. 

Both the need to reduce experimental costs and increasing reHabiHty of mathematical modeling have led to growing acceptance of computer-aided process analysis and simulation, although modeling should not be considered a substitute for either practical experience or reHable experimental data. 

The standard requires the supplier to have the appropriate resources and equipment (when specified in the contract) to utilize computer-aided product design, engineering, and analysis that is compatible with the customer s and subcontractor systems. It is also required that the supplier be able to use numerical design and drawing data, by computer-aided methods for the manufacture of production tooling and prototypes. 

Within the pharmaceutical industry we have progressed from the point where computers in the laboratory were rarely present or used beyond spreadsheet calculations. Now computers are ubiquitous in pharmaceutical research and development laboratories, and nearly everyone has at least one used in some way to aid in his or her role. It should come as no surprise that the development of hardware and software over the last 30 years has expanded the scope of computer use to virtually all stages of pharmaceutical research and development (data analysis, data capture, monitoring and decision making). Although there are many excellent books published that are focused on in-depth discussions of computer-aided drug design, bioinformatics, or other related individual topics, none has addressed this broader utilization of... 

GC-Computer System Nowadays, a large number of data-processing-computer-aided instruments for the automatic calculation of various peak parameters, for instance relative retention, composition, peak areas etc., can be conveniently coupled with GC-systems. A commercially available fairly sophisticated computer system of such type are available abundantly that may be capable of undertaking load upto 100 gas-chromatographs with ample data-storage facilities. In fact, the installation such as multi GC-systems in the routine analysis in oil-refineries and bulk pharmaceutical industries, and chemical based industries have tremendously cut-down their operating cost of analysis to a bare minimum. 

Despite these problems EST databases are a valuable source of large-scale analysis of human variation. They will become even more valuable as the data continue to grow at the present rate. An algorithm for computer-aided SNP mining should contain filters to eliminate the potential sequence errors. Such filters can be based on the probabilistic analysis of sequence features. It can also take into account that multiple occurrences of a variant are more trustworthy, and it may furthermore focus on improving the quality of base-calling if the fluorescent traces are available for closer srcutiny. 

Ethylene. Reactions occurring in mixtures containing 03 and C2H4 in the ppm concentration range in air have been examined by Su et al. [123] and by the authors group [124]. A major product, previously unidentified (compound X), was detected, and the kinetic and spectroscopic characterization of this compound was attempted. The representative spectral data and the results of the computer-aided data analysis are illustrated in Figures 14-16. 

J.R. Llinas, J.M. Ruiz, Multivariate analysis of chemical data sets with factorial methods , in Vernin G., Chanon M. (eds.) Computer aids in chemistry , Ellis Horwood Limited, Chichester, England (1986). p.200,... 

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