Anaerobiospirillum

Lee, P.C., Lee, W.G., Lee, S.Y. and Chang, H.N. 2001. Succinic Acid Production with Reduced By-Product Formation in the Fermentation of Anaerobiospirillum Succiniciproducens Using Glycerol as a Carbon Source. Biotechnol. Bioeng., 72, 41 —48. 

Anaerobiospirillum succiniciproducens ATCC 53488 Anaerobic batch process in complex medium on 80 1-scale 1.37 180 9 109 (205) 0.26 Glassner and Datta (1992)... 

Lee PC, Lee WG, Kwon S, Lee SY, Chang HN. (2000). Batch and continuous cultivation of Anaerobiospirillum succiniciproducens for the production of succinic acid from whey. Appl Microbiol Biotechnol, 54, 23-27. 

Lee PC, Lee WG, Lee SY, Chang HN. (2001). Succinic acid production with reduced byproduct formation in the fermentation of Anaerobiospirillum succiniciproducens using glycerol as a carbon source. Biotechnol Bioeng, 72, 41-48. 

Lee PC, Lee SY, Hong SH, Chang HN, Park SC. (2003b). Biological conversion of wood hydrolysate to succinic acid by Anaerobiospirillum succiniciproducens. Biotechnol Lett, 25, 111-114. 

Lee PC, Lee SY, Chang HN. (2010b). Kinetic study on succinic acid and acetic acid formation during continuous cultures of Anaerobiospirillum succiniciproducens grown on glycerol. Bioprocess Biosyst Eng, 33, 465 71. 

Rifkin GD, Opdyke JE. (1981). Anaerobiospirillum succiniciproducens septicemia. J Clin Microbiol, 13, 811-813. 

Samuelov NS, Lamed R, Lowe S, Zeikus JG. (1991). Influence of COj-HCOj" levels and pH on growth, succinate production, and enzyme activities of Anaerobiospirillum succiniciproducens. Appl Environ Microbiol, 57, 3013-3019. 

Samuelov NS, Datta R, Jain MK, Zeikus JG. (1999). Whey fermentation hy Anaerobiospirillum succiniciproducens for production of a succinate-hased animal feed additive. Appl Environ Microbiol, 65, 2260-2263. 

Succinic acid can be produced by anaerobic fermentation of several wild-type strains Anaerobiospirillum, Propionibacterium, Escherichia,Pec-tinas. Succinie aeid is eonsidered as one of the major bio-based platform ehemieals (Figure 1.9). Its applieations are foreseen as well in commodity chemicals (THF, hydrojgrsuccinimide etc.), as organic acids (malic, fumaric, itaconic etc.) or polymers (polybutylene succinate, PBS). ... 

Succinic acid Actinobadllus succinogenes Mannheimia succiniciproducens E. coli Anaerobiospirillum succiniciproducens 16,000/-... 

Figure 17.2 Anaerobic metabolic pathways involved in SA production in wild-type Anaerobiospirillum succiniciproducens. PEP, phosphoenolpyruvate OAA, oxaloacetate MAE, malate FUM, fumarate El, nonspecific protein of the phosphotransferase system (PTS) HPr, non-specific phosphoryl carrier protein of PTS pyk, pyruvate kinase pfo.

Jabalquinto, A.M., Laivenieks, M., Gonzalez-Nilo, F.D., Encinas, M.V., Zeikus, G., and Cardemil, E. (2003) Anaerobiospirillum succiniciproducens phosphoenolpyruvate carboxykinase mutagenesis at metal site 2. J. Protein Chem., 22, 515-519. 

Lee, P.-C., Lee, S.-Y, and Chang, H.-N. (2008) Cell recycled crrltirre of succinic acid-producing Anaerobiospirillum succiniciproducens using an internal membrane filtration system. /. Microbiol. Biotechnol, 18, 1252-1256. 

Anaerobiospirillum succiniciproducens is another high succinate producer that has been the focus of several patents and process development. One patent describes a method for... 

Anaerobiospirillum succiniciproducens is a strict anaerobe and grows at an optimal temperature of 39 °C. A typical fermentation medium contains dextrose, peptone, yeast extract, and salts. The optimal pH range for this organism was determined to be between 5.8 and 6.4. This organism can produce approximately 30 g of succinate/1 fi-om a starting glucose concentration of 50 g/1. Calcium hydroxide is added to produce a calcium succinate product, which can be precipitated fi-om the broth (Datta 1992). 

Michigan Biotechnology Institute US 5521075 1996 Anaerobiospirillum succiniciproducens Fermentation... 

None cited US 5143833 1992 Anaerobiospirillum succiniciproducens Downstream purification... 

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