Anabolism, concepts

Evans NA. Current concepts in anabolic-androgenic steroids. Am J Sports Med. 2004 32 534-542. 

Chemistry Linirs to Health apply chemical concepts to relevant topics of health and medicine such as weight loss and weight gain, trans fats, anabolic steroids, alcohol abuse, blood buffers, kidney dialysis, and cancer. 

Millward DJ, Rivers JP The need for indispensable amino acids the concept of the anabolic drive. Diabetes Metab Rev 1989 5 191-211 (review). 

In the past few years, the increasing refinement of experimental techniques in the study of the biosynthetic pathways of nucleic acids and proteins has considerably enhanced our understanding, at the molecular level, of the anabolism of these two classes of macromolecules. The experimental approaches have been numerous and diversified, so many of these new concepts can be accepted with a high degree of confidence. 

The hierarchy that characterizes life is maintained through a multiplicity of catabolic and anabolic reactions, governed by a complex set of mechanisms that control the rate and timing of these processes. Thus, while this book will focus primarily on intermediary metabolism and its control mechanisms, in this chapter we will consider metabolic control from the viewpoint of nonlinear, nonequilibrium thermodynamics, which deals with the issue of how molecular events can be coupled and amplified so that they are expressed on a macroscopic level. The concepts herein expressed may be difficult to grasp at first reading. With perseverance, the beauty of the concepts will become apparent and their great importance for biological systems will become evident. 

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