An Example of Raman Hyperspectral Imaging Analysis

Empirical Approach to Successful Raman Hyperspectral Imaging 

The goal of Raman hyperspectral imaging analysis is to obtain chemical images which provide both chemical and spatial characterization of the sample. In an ideal world, each of the chemical components is identified and its distribution visualized the analysis results then also provide the statistical and quantitative results. 

A typical pharmaceutical sample contains both active and inactive ingredients that are combined into a form that can easily be delivered, such as tablets, injection solutions, transdermal patches or implants. Most often, the active ingredients have 

Figu re n.5 Raman images of an over-the-counter (OTC) analgesic tablet with (a) 100 im step over 800 x 800pm and (b) 10pm step over 400 x 400pmf 

Figu re n.6 Schematic diagrams for (a) point mapping and (b) DuoScan mapping the same area at the same step size. The colored circles represent materials of interest, (a) Small circles represent laser focus (b) Small squares represent pixels. 

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