4-Amino-5-chloro-2-phenyl-3-pyridazon

There are few reports of the nitration of the pyridazines and pyrazines. The nitration of phenylpyridazines has been stated to occur exclusively in the phenyl ring (73MI1). The use of fuming nitric acid at 0°C forms only the 4-nitrophenyl derivative (95%), as does 4-chloro-2-phenyl-3-pyridazone (100%), and 4-amino-2-phenyl-3-pyridazone (60%) (47JCS549). 

PHENOSANE 1-PHENYL-4-AMINO-5-CHLORO-PYRIDAZON-(6) (GERMAN) 1-PHENYL-4-AMINO-5-CHLOROPYRIDAZONE-6 1-PHENYL-4-AMINO-5-CHLORO-6-PYRIDAZONE PYRAMINE PYRAMIN RB PYRAZON PYRAZONE PYRAZONL... 

CAS 1698-60-8 EINECS/ELINCS 216-920-2 Synonyms 5-Amino-4-chloro-2,3-dihydro-3-oxo-2-phenylpyridazine 5-Amino-4-chloro-2-phenyl-3-(2H)-pyridazinone 1-Phenyl-4-amino-5-chloro-6-pyridazone 1 -Phenyl-4-amino-5-chlorpyridaz-6-one Pyrazon Classification Pyridazinone Empirical CioHsCINsO... 

Phenyl-4-amino-5-chloro-6-pyridazone 1-Phenyl-4-amino-5-chlorpyridaz-6-one. See Chloridazon... 

Crathome [16] reported a method for the determination of Pyrazon (5-amino-4-chloro-2-phenyl-3-pyridazone) in non saline waters. Pyrazon was isolated from water samples (500mL) by rotary evaporation to dryness in vacuo, extraction of the solid residue with methanol (2><25mL) and further evaporation of the methanol extract (to approx. 2mL). Final concentration (to 0.5mL) was achieved by removal under a stream of nitrogen. 

The herbicidal properties of the pyridazine group were described by Fischer in 1962, and the first of them, pyrazon, 5-amino-4-chloro-2-phenyl-3-pyridazone (1), was introduced in 1962 by the BASF AG under the trade name Pyramin . 

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