Amines and Their Derivatives Functional Groups Containing Nitrogen

Amines and Their Derivatives Functional Groups Containing Nitrogen 

21-4 Physical, Spectroscopic, and Acid-Base Properties of Amines Qualitative and quantitative characteristics of the functional group. 

Mostly extensions of earlier material a couple of special reactions, too. 

By the way. all these nice, tidy analogies do not extend to the smells possessed by most amines. Whereas alcohols tend to have, at worst, somewhat heavy, sweetish odors, amines, at best, smell like ammonia, and, at worst, richly deserve the common names that have been bestowed upon some of their representatives. These include names like cadaverine. putrescine. and skatole. Dead fish would be an improvement. 

The acid-base properties of amines are an extension of what you know about ammonia They are weaker acids and stronger bases than are water or alcohols. It will repay you many times over, however, to go over the information involving pAS/s of these molecules. The qualitative ability to handle acid-base concepts is one of the more useful capabilities you can take out of a course in organic chemistry. 

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S6 21 Amines and Their Derivatives Functional Groups Containing Nitrogen... 

Chapter 21 AMINES AND THEIR DERIVATIVES FUNCTIONAL GROUPS CONTAINING NITROGEN... 

Mannich bases derived from polynitroalkanes are usually unstable because of the facile reverse reaction leading to stabilized nitronate anions. The nitration of Mannich bases to nitramines enhances their stability by reducing the electron density on the amine nitrogen through delocalization with the nitro group. The nitration of Mannich bases has been exploited for the synthesis of numerous explosives, some containing both C-NO2 and N-NO2 functionality. Three such compounds, (163), (164) and (165), are illustrated below and others are discussed in Section 6.10. 

Amines and amides are derived from ammonia and contain nitrogen in their functional groups. Figure 14-13 shows the amine and amide functional groups. 

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