Amides macrocyclic imides

Amides and imides. The photochemical decarbo>ylation of acryloylojy-substituted long-chain carboxylic acids opens a path to macrocyclic lactams through radical photocyclization. Pyrrolyl and indolyl benzoxazoles have been obtained from the intramolecular O arylation in photostimulated reactions.The photocyclization of the... 

A useful method to synthesize ten and fourteen-membered ring imides 346 involved an initial condensation of macrocyclic -ketoestes 343 with alkyl or aryl isocyanates and carbodiimides, respectively, in the presence of a base [68]. After a nucleophilic attack of the enolate on the isocyanate C, the resultant amide N anion 344 induced a ring closure by addition to the keto group. Then, the intermediately formed four-membered ring 345 underwent a fragmentation... 

Cyclic amines (including local anesthetic drugs) and amides were among the first classes of chiral compounds investigated in the early stages of the application of macrocyclic antibiotics as chiral selectors therefore, they were screened on vancomycin [7], teicoplanin [30], and ristocetin A [33] CSPs, under RPmode systems. Cyclic imides (including barbiturates, piperidine-2,6-diones, and mephenytoin) have been separated on a vancomycin CSP [157], under NP and RP mobile phase conditions. 

A reactive macrocyclic ether-urethane carbodiimide (MC-CDI), which is the key intermediate for synthesizing poly(amide-urethane) and poly(amide-imide-urethane), was prepared by the sequential self-repetitive reaction. A se-... 

Metalloporphyrins and metallocorroles have been shown to acts as alkene aziridina-tion catalysts, and the extent of macrocycle halogenation has been shown to correlate with catalyst performance. Mn(III) complexes of 5,10,15-Tris(pentafluorophenyl) corrole are active in aziridination catalysis [101, 102] electron-withdrawing substituents on the corrole are required to facilitate amide transfer to the alkene. Fluorination of corroles also leads to stable metal imide intermediates during aziridination reactions. 

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