Benzene, alkyl subs

Benzene, alkyl subs, 85, 87, 89, 223 Benzene, bromo subs, 85 Benzene, chloro subs, 85, 87, 223, 293 Benzene, cyano subs, 88 Benzene, disubs (mixed ligands) 86, 89 Benzene, hydroxy subs (phenols) 85, 83, 84, 85... 

N-Methylacetanilide is obtained in 96% yield by the action of methyl iodide or dimethyl sulfate on the sodium salt of acetanilide. The last compound is prepared from acetanilide and sodium wire in hot benzene. The reaction has been extended to other aliphatic and aromatic N-sub-stituted amides. Sodium hydride serves to convert the amide to its salt, and a variety of simple halides have been successfully employed as alkylating agents, ... 

Table 2.15 summarizes the main reactions of industrial interest in the liquid and vapor phases, the type of catalysts used, conversions and selectivities in the industrial processes. While O2 is the only oxidizing agent in the second sub-class (apart from the recent case of benzene hydroxylation to phenol using N2O as the oxidant), O2 and oxygen transfer agents (alkyl hydroperoxide or H2O2) are used in the liquid phase. 

There is also a correlation of C NMR chemical shifts of the a- and p-carbons of di- and tri-sub-stituted a,p-unsaturated acids, represented by the empirical relation in equations (2a) and (2b), which relies on the additive shielding increments Another method used for the determination of double bond configuration makes use of effects induced by benzene or other aromatic solvents on the chemical shifts of double bond substituents preferential shielding of protons or alkyl groups trans to the polar groups is usually observed. An example of the use of this method is the determination of the stereochemistry of the double bond in (Z)- and ( -geranic acids (6 and 7 Scheme 6). ... 

---