Aleutian disease

Cucumariosides from C. japonica showed also antiviral activity [103, 104]. Cucumariosides demonstrated a restorative effect in mink infected by Aleutian disease virus [103]. The authors suggested that the effect of the cucumariosides may be related to the increased interaction of T- and B- lymphocytes and humoral... 

Aleutian disease (Mink autoimmune disease) Ho,E,C,l Cholinesterase/butyryl thiocholine Hg-film electrode 1 -7 nM, specific Ab 95... 

Solutions of glutaraldehyde (2%) and formaldehyde (8%) have been shown to be effective against porcine parvovirus after 20 minutes, and pseudorabies and transmissible gastroenteritis viruses after 5 minutes exposure [169]. Aleutian disease virus of mink was inactivated by formalin only after 30 minutes exposure, but glutaraldehyde inactivated 4-log of infectious virus within 5 minutes at 23°C [170]. Formalin (0.2%) was found to be ineffective... 

Aleutian Disease of Mink A Model for Persistent Infection... 

Disorders similar to CHS in humans have been reported in beige mice, Aleutian mink, Hereford cattle and killer whales, and neutrophil dysfunctions similar to those reported in humans are apparent in these animals. Therapy of CHS in humans usually consists of careful management of infections with appropriate antibiotics, although improvements have been reported following administration of high doses of ascorbic acid. Bone-marrow transplantation offers some hope to these patients, especially those entering the accelerated phase of the disease. 

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