Alcohols aridity

Possetto s method of testing 1 is as follows To 250 c.c. of boiling water contained in a porcelain dish are added first 20 c.c. of 95% alcohol arid 2 c.c. of 10% ammonia solution and immediately afterwards 30 grams of the material. After about 5 minutes boiling—when it is considered that the liquid is sufficiently coloured—cold water is added and the solid allowed to settle. The liquid is decanted into another dish and, after slight acidification with 10% hydrochloric acid, a small skein of defatted wool (0-5 gram) boiled in it for 10 minutes. If the wool remains yellow after repeated washing with water, the presence of a coal-tar colour is indicated. 

W lli diliiti aqueous ov alcoholic caustic alkalis, or baryta, 01 sulpluiric arid, a kclonc is foimecl (kctonic decomposition),... 

From intermediate 12, the path to key intermediate 7 is straightforward. Reductive removal of the benzyloxymethyl protecting group in 12 with lithium metal in liquid ammonia provides diol 27 in an overall yield of 70% from 14. Simultaneous protection of the vicinal hydroxyl groups in 27 in the form of a cyclopentanone ketal is accompanied by cleavage of the tert-butyldimethylsilyl ether. Treatment of the resultant primary alcohol with /V-bromosuccini-mide (NBS) arid triphenylphopshine accomplishes the formation of bromide 7, the central fragment of monensin, in 71 % yield from 27. 

The alcoholic ammonia is added to 49 g. (0.16 mole) of di-w-butylaminoethyl bromide hydrobromide (Org. Syn. Coll. Vol. 2, 1943, 92) (Note 1) in a 1-1. round-bottomed flask. The flask is stoppered tightly and allowed to stand for six days at room temperature. The solution is then transferred to an evaporating dish and stirred while it is evaporated to a crystalline paste under a hood. The crystalline paste is transferred to a 400-cc. beaker, and to it is added a solution of 16 g. of sodium hydroxide in 18 cc. of water. The solution separates into an upper layer of brown oil arid a lower layer which contains a considerable amount of undis-... 

Crotonic arid, esterification with sec-butyl alcohol, 41, 60 Crystal Violet, from condensation of oxalyl chloride with dimethyl-aniline, 41, 2-4... 

The denitration system works satisfactorily only for spent acid from the nitration of glycerine and similar alcohols. In spent acid from trinitrotoluene production the high content of dissolved nitrated hydrocarbons causes an excessive reduction of nitric arid at the top of the denitrating tower. Thus spent acid from the nitration... 

A white, crystalline powder,. soluble in wider with tin1 formation of the hydrated arid, IU<)n, hp in,s< liililr in iilwi lute alcohol, other, and carbon [Pg.18]

Empyreumatic Substances. I ee. of mdliyl nleohol should dissolve without turhidily in 0 cc. of wider. On allowing 5 ee. nf roncen I ruled. sulphuric arid In drop inlo 5 ee. of methyl alcohol while kept colt I. lire mixture shun It I not acquire, more t.linu a slightly yellowish color. 

Five grams of the pentammine chloride (No. 119) are triturated with 1% of concentrated sulfuric arid In a mortar placed under the hood hydrogen chloride escapes in considerable quantity. The purple mass is dissolved In 40ml of water (pre-heated to 70°C), and filtered. On coding, the product crystallizes out as reddish prisms. If the mixture is allowed to cool slowly and the product remains under the mother liquor for three days, relatively large crystals can be grown. The salt is filtered, washed with 96% alcohol, and dried at 100°a... 

N-Terminal Amino Arid Sequences of (R)-Alcohol Dehydrogenases from... 

Chloraniline.—Lob 4 has found that p- arid o-chloraniline are obtained by the electrolytic reduction of nitrobenzene suspended in fuming hydrochloric acid, nitrobenzene dissolved in alcoholic hydrochloric acid, and nitrobenzene dissolved in mixtures of hydrochloric and acetic acids. With hydrobromic acid the corresponding bromanilines are formed. 

Piovesta s alcohol oxidase, from the yeast Pichia pastor is. Described as "equally active on methanol and ethanol" (D. Ranasiak arid T. Hopkins, Provest a, personal communication) it is "one-third as active no ethanol than on methanol.." on an enzyme electrode (Hopkins and Muller (in )). The commercial product is virtually devoid of catalase and has a pH stability profile (5. -8. 3) that see/n.s to rule out its use in beer or wines. Alcohol oxidase is still of interest... 

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