Ailanthus excelsa

Hydroxycanthin-6-one (18) has been isolated from the root bark of Ailanthus excelsa (25), the trunk (37) and stem bark (38) of Odyendea gabonensis, the stem bark of Pierreodendron kerstingii (39), and the wood of Simaba multiflora (40). The bathochromic shift caused by alkali addition shown in the UV spectrum together with MS data suggested that... [Pg.145]

Quassinoids.—2 -AcetylgIaucarubine (98) and a new antineoplastic quassinoid, 13,18-dehydroglaucarubinone (99), have been isolated from Simarouba amara. The related 13,18-dehydroglaucarubol-15-isovalerate (100) has been reported from Ailanthus excelsa. The details of the crystal structural analyses of samaderin 7A (101), from Samadera indica, and 6-hydroxypicrasin B (102), from Soulamea species, have appeared. [Pg.200]

Chemical examination of Ailanthus excelsa has been carried out by several workers resulting in the isolation of quassinoids, alkaloids and... [Pg.443]

Khan SA, Shamsuddin KM (1980) Isolation and structure of 13,18-dehydroexcelsin, a quassinoid, and glaucarubol from Ailanthus excelsa. Phytochemistry 19 2484-2485... [Pg.3361]

Species belonging to the Simaroubaceae family are widely referenced in the pharmacopoeias of different medical systems around the world, whether they be of contemporary or ancient use, transmitted orally, or from written sources. For example, Ailanthus altissima, the area of natural distribution of which extends from Manchuria to Malaysia, is one of the most cited species in ancient Chinese medical treatise for a wide range of indications. One of the oldest recipes for this species has been recorded in a book in China dating back to 732 AD for the treatment of mental illness [110]. Its bark is stiU registered in actual Chinese and Asian pharmacopoeias, and it is traded across China. The same applies to Brucea javanica fruits in Southeast Asia and to Ailanthus excelsa Roxb. bark, mentioned in ancient and contemporary ayurvedic medicine books [111]. The use of Brucea antidysenterica bark has also been documented since the sixteenth century in ancient Arabic medical pharmacopoeias [112]. [Pg.3791]

Ailanthus excelsa Roxb. (India) Asthma (SBk), antispasmodic (gastro-intestinal) (SBk) [117] ... [Pg.3793]

Lavhale MS, Kumar S, Mishra SH, Sitasawad SL (2009) A novel triterpenoid isolated from the root bark of Ailanthus excelsa Roxb (Tree of Heaven), AECHL-1 as a potential anticancer agent. PLoS One 4 e5365... [Pg.3800]

Khare CP (ed) (2004) Indian herbal remedies. Springer, Berlin, p 522 Kumar D, Bhat ZA, Singh P, Bhujbal SS, Deoda RS (2011) Antihistaminic activity of aqueous extract of stem bark of Ailanthus excelsa Roxb. Pharmacogn Res 3 220 Dhanasekaran S, Suresh B, Sethuraman M, Rajan S, Dubey R (1993) Antifertility activity of Alianthus excelsa Linn, in female albino rats. Indian J Exp Biol 31 384... [Pg.3801]

Ailanthus altissima is a tall deciduous tree of Chinese origin. A study of the wood extractives has revealed the presence of three alkaloids canthin-6-one, can-thin-6-one-3-oxide, and l-methoxycanthin-6-one (118). Another member of the same family, Simarouba amara, contains 5-hydroxycanthine-6-one (93). The root bark of Ailanthus excelsa contains four canthine derivatives canthin-6-one, 1 -methoxycanthin-6-one, 5-methoxycanthin-6-one, and 8-hydroxanthin-6-one (27). [Pg.227]

Cordell G A, Ogura M, Farnsworth N R 1978 Alkaloid constituents of Ailanthus excelsa (Simaroubaceae). Lloydia 41 166-168... [Pg.251]

Gris (58). 13,18-Dehydroglaucarubinone (36b) was found in Simarouba amara (91) and in Ailanthus altissima (36), 13,18-dehydroailanthinone (37b) in Pierrodendron kerstingii (46) and 13,18-dehydroexcelsin (38) was found in Ailanthus excelsa (40) and in A.malabarica (39). Only those quassinoids which possess an a, 3-unsaturated ketol group in ring A display significant antineoplastic activity in the NIH murine lymphocytic leukemia P 388 (PS) system. [Pg.229]

Acetoxyglaucarubine (32b) Excelsin (33) C27H38O11 C25H36O9 538 480 Simarouba amara Ailanthus excelsa Odyendyea gabonensis 246° + 29.5° (91, 112) (40, 112)... [Pg.256]

Khan, S. A., S. S. Zuberi, and K. M. Shamsuddin Isolation and Structure of Excelsin, a New Quassinoid from Ailanthus excelsa. Indian J. Chem. 19B, 183 (1980). [Pg.261]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...