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Free radical aging theory

Adamantyl haUdes, reactions of 677 p-(l-Adamantyl)phenols, synthesis of 606, 607 Aerophobin-1, biosynthesis of 1315, 1316 Aeroplysinin-1, synthesis of 1327, 1328 Aerothionin, biosynthesis of 1315, 1316 Ageing, free-radical theory of 140, 141 Agent Orange 12... [Pg.1477]

Since Harman s famous work [440] on free radical theory of aging in 1956, numerous studies have been dedicated to the development of his theory, which were reviewed by many authors (see, for example, early reviews, Refs. [441-444]). There is of course no necessity and possibility to discuss these reviews, which have been perfectly considered by their authors. [Pg.945]

Harman, D., The free radical theory of aging the effect of age on serum mercaptan levels, J. Gerontol. 15, 38 10, 1960. [Pg.664]

In-depth studies of the accelerated aging syndromes, especially Down s syndrome, will further clarify the relationship between the genomic and free radical theories. [Pg.49]

H7. Harman, D., Free radical theory of aging Role of free radicals in the origination and evolution of life aging and disease process. In Aging and Degenerative Disease Processes. Alan R. Liss, New York, 1996. [Pg.238]

Harman, D., The Free Radical Theory of Aging Effect of Age on... [Pg.257]

Harman D. Hendricks, S, Eddy DE. Seibold J. Free radical theory of aging effect of dietary fat on central nervous system function.. 1 Am Gerialr Soc 1976 24 301-307. [Pg.232]

Pacific RE, Davies KJA (1991) Protein,lipid, and DNA repair systems in oxidative stress the free radical theory of aging revisited. Gerontology 37 166-180... [Pg.72]

Beckman KB, Ames BN (1998) The free radical theory of aging matures. Physiol Rev 78 547-581... [Pg.232]

B. (2008) The mitochondrial free radical theory of ageing-where do we stand Front. Biosci., 13, 6554-6579. [Pg.16]

Birds are an ideal test case for the hypothesis that it is the rate of free-radical production, rather than some other facet of metabolism, that is linked to longevity. If lifespan is linked to metabolism in a general sense, then we would expect free-radical production to vary with metabolic rate in all cases, as indeed it does in most mammals. On the other hand, if free radicals are responsible for ageing, the fact that birds consume so much oxygen can only mean that they have a very efficient mechanism for cutting down free-radical production. Put another way, if the free-radical theory is correct, birds must produce fewer free radicals than mammals, even though they consume far more oxygen. [Pg.255]

The mitochondrial theory of ageing was first proposed by Denham Harman, author of the free-radical theory, as a refinement of his original... [Pg.263]

Partly because cancer incidence is strongly correlated with age, many scientists also attribute normal aging to the accumulation of unrepaired mutagenic DNA lesions, and oxidative stress is implicated in what has been called the "free radical theory of aging."... [Pg.1747]

Harman, D. (1992) Free radical theory of aging. Mutat. Res. 275 257-266. [Pg.490]

Among the numerous theories raised to explain ageing, the free radical theory of ageing has become especially relevant (Harman 1956, Sohal 1984,... [Pg.661]

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