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Agelas nakamurai

Agelas nakamurai from Japan produced the sesquiterpene sulfone, agelasidine A (353), which possessed antispasmodic activity. The structure was deduced from spectral data [309]. A simple synthesis of agelasidine A (353) utilised a hetero-Claisen rearrangement [310]. A biomimetic synthesis of 353 was also reported [311] and another synthesis of agelasidine A (353) was carried out in three steps from famesol [312]. [Pg.670]

Bromopyrrole-2-carbamide (116) was isolated from the Papua New Guinean sponge Agelas nakamurai. It exhibits antimicrobial activity against Staphylococcus aureus (IC50 0.78 pg/ml) and other bacteria and fungi [92]. [Pg.780]

Most of the known natural brominated pyrrole alkaloids are found in sponges, and several new examples were isolated since the first survey (1). Reviews are available that discuss the occurrence and syntheses of these metabolites (1236-1238). The Papua New Guinea sponge Agelas nakamurai has yielded the new simple pyrroles 1222 and 1223 (1239). The dibromo analog (1224) of 1223 along with enantiomeric lactams 1225/1226, which were separated by chiral HPLC, and... [Pg.183]

Iwagawa T, Kaneko M, Okamura H, Nakatani M, van Soest RWM (1998) New Alkaloids from the Papua New Guinean Sponge Agelas nakamurai. J Nat Prod 61 1310... [Pg.436]

Uemoto H, Tsuda M, Kobayashi J (1999) Mukanadins A-C, New Bromopyrrole Alkaloids from Marine Sponge Agelas nakamurai. J Nat Prod 62 1581... [Pg.437]

Meketa ML, Weinreb SM (2006) Total Synthesis of Ageladine A, an Angiogenesis Inhibitor from the Marine Sponge Agelas nakamurai. Org Lett 8 1443... [Pg.438]

Mukanadins A (10) and B (12) have been isolated from the Okinawan sponge Agelas nakamurai [33] actually, the structure of mukanadin A corresponds to that of... [Pg.275]

Two sceptrin-related compounds, nakamuranic acid (73) and its corresponding methyl ester (74), have been isolated from the Indo-Pacific sponge Agelas nakamurai [114,115],... [Pg.288]

Several simple bromopyrroles (101-109) have been isolated from Agelas oroides (101, lOS) [129,1], Agelas flahelliformis (101, 102) [130], AoantheUa carteri (103, 104) [131], Agelas nakamurai (106, 107) [132], Homoaxinella sp. (108) [133], and AxineUa... [Pg.291]

Ageladine A (84), from the sponge Agelas nakamurai, is the first isolated pyrrole-imidazole alkaloid containing a 2-aminoimidazolopyridine moiety [78]. [Pg.164]

Meketa, M. L. Weinreb, S. M. 2006. Total synthesis of ageladine A, an angiogenesis inhibitor from the marine sponge agelas nakamurai. Org. Lett. 8 1443-1446. [Pg.803]

See other pages where Agelas nakamurai is mentioned: [Pg.670]    [Pg.688]    [Pg.712]    [Pg.184]    [Pg.185]    [Pg.187]    [Pg.190]    [Pg.438]    [Pg.59]    [Pg.59]    [Pg.60]    [Pg.277]    [Pg.295]    [Pg.1164]    [Pg.343]    [Pg.53]    [Pg.56]    [Pg.158]    [Pg.196]    [Pg.200]    [Pg.164]    [Pg.165]   
See also in sourсe #XX -- [ Pg.670 ]

See also in sourсe #XX -- [ Pg.688 , Pg.712 , Pg.780 , Pg.860 ]

See also in sourсe #XX -- [ Pg.6 , Pg.25 , Pg.28 , Pg.670 , Pg.688 , Pg.712 , Pg.780 , Pg.860 ]

See also in sourсe #XX -- [ Pg.164 , Pg.165 ]



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Agelas

Agelas nakamurai agelasin-B from

Agelas nakamurai antispasmodic activity

Agelas nakamurai structure

Agelas nakamurai triphosphate ase inhibitor

Agelas nakamurai, ageladine

Sponges Agelas nakamurai

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