Agelas nakamurai structure

Agelas nakamurai from Japan produced the sesquiterpene sulfone, agelasidine A (353), which possessed antispasmodic activity. The structure was deduced from spectral data [309]. A simple synthesis of agelasidine A (353) utilised a hetero-Claisen rearrangement [310]. A biomimetic synthesis of 353 was also reported [311] and another synthesis of agelasidine A (353) was carried out in three steps from famesol [312]. 

Mukanadins A (10) and B (12) have been isolated from the Okinawan sponge Agelas nakamurai [33] actually, the structure of mukanadin A corresponds to that of... 

Wu, H., Nakamura, H., Kobayashi, J., Ohizumi, Y, and Hirata, Y. (1986) Structures of agelasines, diterpenes having a 9-methyiadeninium chromophore isolated from the Okinawan marine sponge Agelas nakamurai Hoshino. Bull. Chem. Soc.Jpn., 59,2495-2504. 

Agelasidines A-D (275-279) are a series of terpene derivatives of hypotaurocyamine and were isolated from sponges of the genus Agelas. Agelasidine B (276) and (+)-C (277) were obtained from the Okinawan A. nakamurai [201] while agelasidines (-)-C (278) and D (279) were isolated from the Caribbean A. clathrodes [202]. The structures of these compounds were elucidated by interpretation of spectral data and by... 

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