Ageing population, clinical

Enhancement of the human HS response may eventually be a clinical goal in dealing with the aging population which may be more susceptible to environmental stress. Several investigators have now shown an age-dependent defect in the regulation of the HS response at the transcriptional level (Fargnoli et al., 1990). This defect has been observed in human peripheral blood lymphocytes and in... 

Abernethy, DR. Research challenges, new drug development, prechnical and clinical trials in the ageing population. Drug Safety 1990 5 71. ... 

The growth of the aging population, regulatory overview and increased business opportunities will ensure the growth of clinical research in the elderly. Recent reports of the high level of seniors adverse events, many leading to deaths, both in and... 

In clinical applications, the best recommendation for testing available applications would be to use a case-based methodology. We recommend that five or six complicated cases, which would represent a cross section of the patient population served by the pharmacy, be used to test the application. In this way, the clinician will see how the application performs throughout an entire care process and avoid the power path demonstration. In this information age, selecting clinical software is an extremely important task. The explosion of capabilities offered by the Internet can make the selection process both exciting and confusing. A careful analysis of options will usually be rewarded by better results, but wary buyers need to prepare themselves to revisit the marketplace more frequently than they might have in the past to identify innovative alternatives. 

Plauchu H, de Chadarevian JP, Bideau A, Robert JM (1989) Age-related clinical profile of hereditary hemorrhagic telangiectasia in an epidemiologically recruited population. Am J Med Genet 32 291-297... 

Most BME research is located in universities, often in collaboration with clinical groups in teaching hospitals. Major research areas include prostheses, non-invasive measurement, biomechanics, and - most appropriately in a country of such vast distances and with an ageing population - rehabilitation, telemedicine, and home healthcare monitoring. 

Once covered with epidermis, the skin is not free from risk of ulcer reccurrence. Chances are the underlying disease, environmental condition or nutritional and health status of the patient have not changed. Continued clinical attention and improvement in the patient s health will ameliorate the risk. However, these incur additional medical costs which are, in this time of aging populations, likely to be significant. By paying particular attention to the quality of healed skin and identifying treatments that help to improve this quality, the chances of reccurrence will be reduced without additional significant medical costs. 

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