Advantage peracetic acid

In the preparation of quinoxaline N-oxides, it is advantageous to use peracetic acid rather than aqueous hydrogen peroxide as the... 

The second important process for propylene oxide is epoxidation with peroxides. Many hydroperoxides have been used as oxygen carriers for this reaction. Examples are t-butylhydroperoxide, ethylbenzene hydroperoxide, and peracetic acid. An important advantage of the process is that the coproducts from epoxidation have appreciable economic values. 

The peroxygen compounds, hydrogen peroxide and peracetic acid, have high killing activity and a broad spectrum against bacteria, spores, viruses, and fungi when used in appropriate concentration. They have the advantage that their decomposition products are not toxic and do not injure the environment. They are powerful oxidizers that are used primarily as disinfectants and sterilants. 

The alkene substrate is first dispersed in the reactor with the carboxylic acid in the presence of a solvent if necessary. Addition of hydrogen peroxide forms the peracid which facilitates epoxidation, and re-generates the carboxylic acid for further reaction. In consequence only low levels of carboxylic acid are required (0.2-0.3 mol per mol of double bond). This also has the advantage of reducing epoxide loss to acid-catalysed ring-opening. The application of two phases with or without the presence of solvent also improves the efficiency of the epoxidation. Peracids most suited to epoxidation in situ are performic and peracetic acid. 

Distilled aqueous peracetic acid is a high purity source of the peracid.40 The major advantages of the distilled aqueous peracetic acid are that it contains no mineral acid, it has a low level of free acetic acid and it has a high water content. The lack of mineral acid and low acetic acid content can have advantages in... 

A variety of organic peroxy acids such as perbenzoic acid, MCPBA. monoperoxyphthalic acid, peracetic acid and trifiuoroperacetic acid are much stronger oxidants dian H2O2, and oxidize sulfides to sulfoxides under very mild conditions. Usually 1 equiv. of peroxy acid to sulfide is employed, otherwise overoxidation easily occurs to give sulfones. Among these, MCPBA has die advantage of being convenient to use and Ae oxidation is normally carried out at 0 C or lower temperatures, in di-chloromethane. The preparations of the base-sensitive sulfoxide (15), a new dienophile alkynyl sulfoxide (16), " and thiiraneradialene S-oxide (17) are typical examples. Selective oxidation of the sulfur atom of penicillins by polymer-supported peroxy acids in DMF or acetone is also known (equation 17). ... 

A third method has the advantage over the two cited in that it is a simple one-step process and that the yield is higher. Iodobenzene (0.1 mole) is stirred at 35° during addition of 0.5 mole of 40% peracetic acid (65 ml.) over a 30-min. period, during which time iodosobenzene diacetate separates. After addition of 80 ml. of... 

Merits and demerits of bleaching with peracetic acid The advantages of peracetic acid as a bleaching agent are ... 

Oxidative Methods. - Corey et al. have reported on the use of the cyclic chromate ester (1) as a catalyst for the peracetic acid oxidation of secondary alcohols. The reagent oxidises primary alcohols very slowly, and is compatible with tetrahydropyranyl protection of alcohols furthermore, it has the great advantage of avoiding the toxicological and disposal problems associated with stoichiometric chromium reagents. The selective oxidation of benzylic alcohols in the presence of... 

One advantage in using alternate oxidants such as Peracetic Acid (PAA) and ammonium bromide is that these oxidants are generally less detrimental to equipment and other chemicals used in papermaking. 

This breakthrough method uses 1,2-trans peracetates in the presence of Lewis acids as a promoter to glycosylate (V -I inoc amino acids with an unprotected a-carboxyl group. The deprotection of that glycosylated amino acid carboxyl group prior to incorporation into a peptide can be avoided (62). In addition, the advantage of this method is that the starting materials are readily available... 

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