Adult mesenchymal stem cells

Steck E et al (2005) Induction of intervertebral disc-like cells from adult mesenchymal stem cells. Stem Cells 23(3) 403 f11... 

Baksh D, Song L, Tuan RS. Adult mesenchymal stem cells characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med 2004 8 301-316. 

Intra-portal infusion of adult mesenchymal stem cells enhances survival of allogeneic beta cells in immunocompetent rats Archambault, M.P., Campbell, S.E., Vanguri, P., McIntosh, K.R. (2002). Blood, 100 11 Abs 2404. 

Another novel cardiovascular therapy that has recently come into play is the use of stem cell delivery. These approaches have thus far involved the use of gene delivery mechanisms to essentially force embryonic stem cells into cardiomyocyte differentiation with the goal of producing a cardiac pace-making cell (Arruda et al., 2004). Researchers are also developing methods for utilizing seeded adult mesenchymal stem cells as an implanted base to act as a depot for the delivery of localized gene therapies (Arruda et al., 2004). 

Table 1 Sources of adult mesenchymal stem cells (MSCs) [32]...

Lee, J., Zhou, Z., Taub, P., Ramcharan, M., Li, Y., Akinbiyi, T., Maharam, E., Leong, D., Laudier, D., Ruike, T., Torina, P., Zaidi, M., Majeska, R., Schaffier, M., Flatow, E., Sun, H., 2011. BMP-12 treatment of adult mesenchymal stem cells in vitro augments tendon-like tissue formation and defect repair in vivo. PLoS One 6. 

Tuan, R. S., G. Boland, and R. Tuli (2003). Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Research and Therapy 5(l) 32-45. 

Belema-Bedada, R, Uchida, S., Martire, A., Kostin, S., and Braim, T. 2008. Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2. Cell Stem Cell, 2, 566-75. 

Izadpanah, R., Kaushal, D., Kriedt, C., Tsien, R, Patel, B., Diifour, J., and Bunnell, B. A. 2008. Long-term in vitro expansion alters the biology of adult mesenchymal stem cells. Cancer Res, 68,4229-38. 

Caplan, A.l. 2007. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. / Cell Physiol 213(2) 341-47. 

Kolf, C.M., Cho, E., and Tuan, R.S. 2007. Mesenchymal stromal cells. Biology of adult mesenchymal stem cells Regulation of niche, self-renewal and differentiation. Arthritis Res Ther 9(1) 204. 

Scotti, C., Tonnarelli, B., Papadimitropoulos, A. et aL 2010. Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc Natl Acad Sd 107 7251-6. 

Collagen-agarose beads Not defined — Adults mesenchymal stem cells —... 

---