Activity against Microorganisms

Because of its antibacterial activity against microorganisms [51-54] and the lack of strains with primary resistance [52, 53], some preliminary studies [174-176] have explored the potential of rifaximin for II. pylori eradication. A first single-blind randomized study [174] evaluated the efficacy of rifaximin alone or in combination in II. pylori-positive patients with antral gastritis and... 

Formaldehyde and glutaraldehyde are used for disinfection or sterilization of instruments such as fiberoptic endoscopes, respiratory therapy equipment, hemodialyzers, and dental handpieces that cannot withstand exposure to the high temperatures of steam sterilization. They are not corrosive for metal, plastic, or rubber. These agents have a broad spectrum of activity against microorganisms and viruses. They act by alkylation of chemical groups in proteins and nucleic acids. Failures of disinfection or steri... 

The oxidative preservatives, in contrast to the chemical preservatives, can be neutralized by mammalian cells and do not accumulate.These preservative systems thus provide effective activity against microorganisms while producing very low toxicity. Both compounds offer significant advantages over traditional preservatives and may produce less cellular toxicity. 

The question of whether or not a polymer-anchored biocide can be active against microorganism growth was first tested by comparing the minimum inhibitory concentrations (MIC) of pentachlorophenol, its acrylate, 8, and the homopolymer of pentachlorophenyl acrylate 8. An agar dilution method was used. To a sterilized agar, a solution of the compound to be tested was added in the appropriate amount to make final concentrations of 1000, 500, 250, 100, 50, and 10 ppm. Following inoculation, the... 

Under this irradiation condition, 02, a molecular species of active oxygen with killing activity against microorganisms, was generated from the dye (Type II mechanism). Emission spectra of O2 generated from dyes under irradiation with a green laser (532 run) were measured by an NIR emission spectrometer that was developed and made in our laboratory (Data not shown). 

These equilibria are discussed more fully with equations 6.18-6.20.) The position of equilibrium is pH-dependent for the fermentation process, the pH is in the range 2.9-3.6. Only molecular 8O2 is active against microorganisms. 

The penicillinase-resistant penicillins [methicillin, nafcillin, oxacillin, cloxacillin, and dicloxacillin] have less potent antimicrobial activity against microorganisms that are sensitive to penicillin G, but they are the agents of first choice for treatment of penicillinase-producing S. aureus and S. epidermidis that are not methicillin-resistant. 

Since the isolation of celastrol in 1936 by Chinese workers a variety of quinonemethides have been encountered in Celastraceae species and their structures and a wide range of biological activities have been reported thus far, resulting quite interesting activities against microorganisms and tumor cells [9,11]. 

In vitro antimicrobial activity against microorganisms pathogenic to man... 

H. Michl could unambiguously show that these peptides are active against microorganisms. 

Antimicrobial soap testing. An antimicrobial soap is a product that contains an active ingredient and has in vitro and in vivo activity against microorganisms residing on the skin. Therefore, the efficacy requirements must examine both the in vitro and in vivo efficacy characteristics of the product. The Antimicrobial I Panel did not provide specific recommendations for the assessment of these products but concluded that the Cade [20] and Quinn [24] handwashing procedures could be applicable to these products. A statement describing the efficacy requirement was not provided. 

The synthesis and study of thiophene oligomers have attracted a great deal of attention for a number of years because of their activity against microorganisms, and recently because of their use as model compounds or... 

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