Activation Properties Reactivity Indices Profiles

On the other hand, nucleophihcity profiles centered at the morpholine moiety (Fig. 7.1b) reveals that at the beginning of the reaction, morpholine interacts in different ways with the substrate (this point is discussed deeply in Section 7.5). Moreover, in this case, nucleophihcity reaches a minimum near the MC for PG and LG moieties, the nucleophihcity reaches a maximum, thereby revealing 

FIGURE 7.1 Reactivity profiles for the reaction between l-halo-2,4-dinitrobenzene toward morpholine, (a) Electrophilicity profiles and (b) nucleophihcity profiles. Adapted with permission from Ormazdbal-Toledo et al. [18]. (2013) American Chemical Society. 

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