Activation, definition

The remarkable efficacy of topical corticosteroids in the treatment of inflammatory dermatoses was noted soon after the introduction of hydrocortisone in 1952. Numerous analogs are now available that offer extensive choices of potencies, concentrations, and vehicles. The therapeutic effectiveness of topical corticosteroids is based primarily on their antiinflammatory activity. Definitive explanations of the effects of corticosteroids on endogenous mediators of inflammation await further experimental clarification. The antimitotic effects of corticosteroids on human epidermis may account for an additional mechanism of action in psoriasis and other dermatologic diseases associated with increased cell turnover. The general pharmacology of these endocrine agents is discussed in Chapter 39. 

The activity definition (17) on the infinite dilution scale, paH = —log- H+ > = —log yH —log[H+] was experimentally studied by Bjerrum and Unmack (4). This definition is not rigid because of the intrinsic uncertainty in defining individual ionic activities. Depending on the precision required, it is usually stated that the approximations used to estimate yH breakdown at some ionic strength between 0.01 and 0.2M. 

Water is added instead of amylase in control experiments. Our enzymatic activity definition is 1 unit of amylase hydrolyses 1.0 mg of starch in 3 min at pH 6.6 at 20°C. 

Levine RD. Free energy of activation. Definition, properties, and dependent variables with special reference to linear free energy relations. J Phys Chem 1979 83(1) 159-170. 

While many of their activities definitely have had a negative impact on humans, mice have also been provided a useful service. Ever since their importation to Europe from Japan in the mid-1900s, house mice, and some other species, have been used as laboratory animals for research in medicine and biology. In particular, mice are used to study human genetics, to test the effects of various drugs, and to follow the development of certain viruses. Eurthermore, mice are used in human pregnancy tests, and they help doctors better understand the way that cancer effects humans. Probably, the most comm on -ly used species is the white mouse, an albino form of the house mouse. 

Activation, definition, 53,55 Activation function, definition, 55 Aeration basin design performance limiting factor, example ofPOTW EXPERT S use, 137-138... 

Cheeseright, T., Mackey, M., Rose, S., and Vinter, A. (2006) Molecular field extrema as descriptors of biological activity definition and validation. Journal of Chemical Information and Modeling, 46 (2), 665-676. 

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