Acetylacetic acid

Vanadium Bis Cyclopentadionyl Acetylacetic-acid Ethyl Ester Perchlorate. 

This value of 07 for acetyl is essentially confirmed by other reactivity-based methods. In 1956 Taft28 gave a value of 0.60 for the 0 constant of CH3COCH2, which was based on his analysis of ester reactivity. When the factor of 0.45 is applied, 0/ for acetyl comes out at 0.27 (Section n.B). In 1964 Charton82 derived a value of 0.29, based on a pKa value of 3.58 for acetylacetic acid (water, 25 °C). Substitution of this pKa value into Charton s later regression equation for substituted acetic acids80 gives 0.299 for the 0/ value of acetyl. 

Boit (97) and Leete (98) suggested that in the biogenesis of pilocarpine, the imidazole compound 47 reacts with acetylacetic acid (48). It should be remarked that the phosphate of 47 is assumed to be an intermediate in the biogenesis of histidine. The reaction between the methylene group in 48 and... 

Later additions to the range were not always derived from the anilide of S-hydroxynaphthoic acid. It was found that other molecular structures were substantive to cellulose and also capable of coupling with diazotized bases. These requirements were fulfilled, for example, by aryl amides of acetylacetic acid such as is illustrated in Naphthol AS.G (C.I. azoic COUPLING COMPONENT 5), (5), where the coupling takes place at the —CHj— groups. 

E.40) Butanoic acid, 3-oxo-, acetoacetic acid, acetylacetic acid Present in traces, but not detectable in all coffee samples (Maier, 1988). 

The esters derived from acetylacetic acid have been realised either from ethy-lacetoacetate by transesterification with l-(2-hydroxyethyl)-3-methylimidazolium tetrafluoborate under MW irradiation [35] or by reaction of hydroxyalkyltrimethy-lammonium salts with a ketene dimer (Scheme 5.5-18) [36]. 

An improved preparation of 1 from the acetal (2) obtained from pivaldehyde and (R)-3-hydroxybutanoic acid, permits preparation of this chiral derivative of acetylacetic acid on a large scale (13 g.). ... 

Essigsaure, Ethansaure (Acetat) acetic anhydride/ ethanoic anhydride/ acetic acid anhydride Essigsaureanhydrid acetoacetic acid (acetoacetate)/ acetylacetic acid/diacetic acid Acetessigsaure (Acetacetat), 3-Oxobuttersaure acetone/... 

Keywords Acetylacetates, 2-Amino-2-deoxyaldoses, Barbituric acids, C-Glyco-sides, Dimedone, Furans, Garcia-Gonzalez reaction, Green chemistry, Hexoses, Meldrum s acid, Penta-2,4-dione, Pentoses, Pyrroles, Reactions in water, Tetrahy-drofuranylfurans... 

The telomerization of dienes in a two-phase system was first described in a patent (100). Water was used as the solvent for the catalyst, with sulfonated phosphane ligands providing the water solubility. Water, alcohols, phenols, acids, amines, and acetylacetic add were used as nucleophiles. 

More interestingly, as an oxidative condition with Mn(OAc)3, various macrolide compounds (230) are obtained in high yields by the treatment of bis(acetylacetate) (228) and bis(olefin) (229) with Mn(OAc)3 in acetic acid under highly diluted conditions (2 mM of substrate) [237,238]. This reaction proceeds as follows. The initial formation of a (3-keto ester radical via single electron oxidation by Mn(OAc)3 and its addition to olefin occur the formed benzylic radical is oxidized by Mn(OAc)3 to form a benzylic cation, then cyclization by oxygen of the enol form of the (3-keto ester occurs, and again this reaction sequence is repeated in another (3-keto ester group to ultimately form the macrolide compounds. 

F.52) Butanoic acid, 3-oxo-, ethyl ester, ethyl acetoacetate, ethyl 3-oxobutanoate, ethyl acetylacetate, acetoacetic acid ethyl ester, diacetic ether (1-41-97-9] FEMA 2415... 

METHYL ACETYLACETATE (105-45-3) Combustible liquid (flash point 170°F/77°C). Moisture may cause decomposition. Incompatible with oxidizers, strong acids, nitrates. 

Acetoacetic Acid. 3-Oxobutanoic acid diaceiic add acetylacetic add acetonecarboxylic acid 3-fcetobutyric acid 2-ketobutyric acid. C4H6Oj mol wt 102.09. C 47.06%, H 5.92%. O 47.02%. CH,COCH2COOH. Prepd by hydrolysis of ethyl acetoacetate Krueger, J. Am. Chem. Soc. 74, 5536 (1952),... 

Methylacetopyronone. See Dehydroacetic acid Methyl 12-acetoxy-9-octadecenoate Methyl 12-acetoxyoleate. See Methyl acetyl ricinoleate Methyl acetylacetate Methyl acetylacetonate. See Methyl acetoacetate Methyl acetylaminobenzoate CAS 2719-08-6 EINECS/ELINCS 220-318-5 Synonyms 2-(Acetylamino) benzoic acid, methyl ester Acetyl methyl anthranilate Acetyl-N-methyl anthranilate Methyl 2-(acetylamino) benzoate Methyl N-acetylanthranilate Empiricai C10H11NO3... 

In 1913, Simonis and co-workers first reported the isolation of the 2,3-dimethyl chromone 5 by reaction of phenol la with ethyl 2-methyl-acetylacetate. While the product was reported in poor yield, the reaction was a change from the typically reported formation of the coumarin. Simonis did report using a different promoter (P2O5) instead of the traditionally used H2SO4 for the Pechmann reaction. For some time, the differences in the two reactions were thought to be that simple sulfuric acid gave the coumarin as reported by Pechmann and phosphorous pentoxide gave the chromone as reported by Simonis. 

Poly(vinyl acetylacetate) Acetic acid, acetone, chloroform, dioxane, DMF, ethyl acetate, pyridine, THF, saturated aqu. sol. of magnesium perdilorate Alcohols, bzn., diethyl ether, W 140... 

---