Acetophenone benzylidene

Tetraazafulvalenes bearing two pyrazole subunits could be prepared by an original way. Tlius, treatment of benzylidene acetophenone with iso-pentylnitrite leads to an A, A -dihydroxy-bipyrazolyl-A, A -oxide, which in turn can be oxidized to TAF of type 100 (72CC961, 79JOC3211). Another type of oxidative dimerization was observed by the reaction of the electron-rich l-methyl-2,4-bis(dimethylamino)imidazole with silver salts (83TL3563). A bis-cation was isolated in 30% yield in the presence of sodium tetrafluo-roborate an unsymmetrical structure 101 was predicted from its NMR data (Scheme 40). 

Benzylacetophenone has been prepared by the reduction of benzalacetophenone with zinc and acetic acid1 and catalytic-ally with palladium and hydrogen 2 by the reduction of /3-duplo-benzylidene acetophenone monosulfide 3 by the oxidation of the corresponding car bind with chromic acid 4 by the hydrolysis of ethyl benzyl benzoylacetate 5 from acetophenone and benzyl chloride by the action of sodamide 6 and from benzoic and hydrocinnamic adds using as catalysts manganese oxide 7 and ferric oxide.8... 

The Michael reaction of benzylidene acetophenone and benzylidene acetone with ethyl acetoacetate, nitromethane, and acetylacetone was studied by Musaliar and co-workers in the presence of a cetyltrimethy-lammonium bromide-containing aqueous micellar medium.50 The Michael reaction of various nitro alkanes with electrophilic alkenes is performed in NaOH (0.025-0.1 M) in the presence of cetyltrimethylam-monium chloride (CTACI) without any organic solvent (Eq. 10.23).51... 

In a lOmL round-bottomed flask equipped with a magnetic stirrer bar were placed tetrahydrofuran (0.8 mL) and immobilized poly-D-leucine (100 mg). (7 )-Benzylidene acetophenone (50 mg), l,8-diazabicyclo[5.4.0] undec-7-ene (90 mg), and urea-hydrogen peroxide (27 mg) were added to the mixture. The thick white reaction mixture was stirred vigorously for 30 minutes. 

An enormous variety of olefinic types have been found to undergo such solid-state (2 + 2) photocyclodimerizations. These include cinnamic acids (128,132) derivatives of cinnamic acids such as esters (133) and amides (134) styrene derivatives (135) stilbenes (136) aliphatic mono- (137), di- (138), and triene (139) dicarboxylic acids and derivatives 1,4-diarylbutadienes (140) and their vinylogs (141), benzylidene acetones (142) and benzylidene acetophenones (143) ... 

Irradiation of powdered complexes of benzylidene acetophenone 43 included in the nonchiral 2 yields a single photoproduct, syn head-tail dimer 44 (Scheme 27) [167,168]. Irradiation of 43 in solution gives a mixture of cis... 

Experiment 6.135 describes the preparation of a range of oc,/ -unsaturated ketones, including benzylideneacetone, furfurylideneacetone and benzylidene-acetophenone. The conversion of this latter compound into /J-phenylpropio-phenone is readily achieved by hydrogenation at atmospheric pressure over an active platinum catalyst. 

Many references to kinetic measurements may have already been covered earlier with other physical methods. These include studies on pseudorotation of stereoisomers of a 10-P-5 spirophosphorane, on the formation rate of acylpho-sphonate hemiketals, on the rate of decomposition of hydroperoxides formed by the oxidation of soya phosphatidylcholine, on the kinetics of the reaction of trimethyl phosphite with benzylidene acetophenones, calorimetric studies on the reaction kinetics of dithiophosphoric acid 0,0 -dialkyl esters with zinc oxide, " and the kinetics of selective dephosphorylation of 2 -phosphorylated and 2 -thiophosphorylated dinucleotides. 

Diamino-4-phenylimidazole reacts with aromatic a,/3-unsaturated ketones in an acidic medium to yield triazepines 436 (83KGS93). If the reaction is carried out in alkaline medium with benzylidene acetophenone,... 

The limits to the applicability of this selective reduction method are shown by the hydrosiiyiation of PhCH==CHCOPh or l,3-diphenylprop-2-en-l-one, benzylidene-acetophenone, or cinnamoylbenzene, which proceeds only by 1,4-addition even when dihydrosilanes and trihydrosilanes are employed . However, selective 1,2-addition is achieved by using CsF as catalyst" ... 

Dithiins are produced by the reactions of geminal dithiols with enones such as chalcone and benzylidene acetophenone (Equation (54)) <62JOC4488, 66BSF1920>. Treatment of geminal dithiols with malononitrile also gives rise to 1,3-dithiins (Equation (55)) <62JPR2ll>. 

Acrylophenone, 3-phenyl- AI3-00946 Benzalaceto-phenone 2-Benzalacetophenone 1-Benzoyl-1-phenylethene 1-Benzoyl-2-phenylethene Benzylidene acetophenone 2-... 

Kohler showed188 that <%,/ -unsaturated ketones undergo both 1,2-addition of Grignard reagents to the carbonyl group and 1,4-addition to the conjugated system thus eo,co-diphenylpropiophenone is obtained from benzylidene-acetophenone and phenylmagnesium bromide ... 

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