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This book is intended to provide an overview of several areas of research in which amination plays a key role, and to introduce the reader to new concepts that have been developed quite recently for generating new C - N bonds. As the pharmaceutical and chemical industries move rapidly away from the development of racemic compounds, the access to synthetic routes that lead efficiently to enantiomerically pure materials is becoming increasingly important. For this reason, most of the contributions in this book refer to asymmetric synthesis. However, no attempt has been made to present a comprehensive work, and important areas such as asymmetric hydroxyamination [1] have not been dealt with. Furthermore, it may be worth mentioning that viable, useful and comprehensive sources of information about the methodological approaches to electrophilic amination developed since 1985 have already been reported [2], and that a chapter in Houben-Weyl reviewing several aspects of the asymmetric electrophilic amination [3] compiles important contributions up to 1995. [Pg.275]

This chapter is devoted to the properties of polymeric gel-forming liquids. Particulate gels are discussed in Chapter 7. The structure of a polymeric gel is sketched in Fig. 5-1. Since this book is devoted to materials that are in some sense liquid, or at least liquefiable, we shall not say much about hard, irreversible, chemical gels such as cured epoxies or vulcanized rubber, but shall focus instead on chemical pre-gels and thermally reversible physical gels, both of which can be considered borderline fluids. This chapter is confined to a brief overview. Much more detail can be found in Winter and Mours (1997), and volume 101 of the Faraday Discussions. ... [Pg.232]

This book, therefore, is a self-contained introduction to the discipline of Statistics and its use in therapeutic confirmatory clinical trials. The first part of the book provides introductory comments about the discipline of Statistics and lays the foundations for our later discussions in the context of pharmaceutical trials. Chapter 2 presents an overview of the process of new drug development and the role of clinical trials in this process. The categories of different types of clinical trials are identified and discussed so that you will understand thetypes of data collectedin them. [Pg.6]

An area of considerable mleresi and the focus of many research projects is the antioxidant properties of spices. As was mentioned earlier, one of the earliest uses of spices was to help preserve foods. Little was understood at that time about the mode of action of the spices. It was simply known that they would help maintain the quality of the food to be stored. The area of antioxidant properties of spices is important for preserving the quality of foods but may also provide beneflcial health effects for people consuming the spices. This area will be covered in much more detail in an overview of the antioxidant properties of spices that is presented later in this book in the chapter by Madsen et a). One spice component in particular that lias received attention is curcumin. SeveraJ chapters address the eifectiveness of curcumin and possible ways to synthesize new curcuminoids. The investigators have looked at the various ways in which the compounds may be effective as an antioxidant in different sterns. This is an area that wifi continue to receive attention in the lesearch community as people continue to look for the specific health benefits that certain foods may offer. Spices will remain important for the flavor that they impart to foods and may also gain significance for other benefits they have to offer... [Pg.9]

You have just read about the math topics covered in this book. To mimic a real test environment, math concepts are mixed within each section. For example, in the arithmetic section, you may find a question or two on exponents, then three questions on square roots, followed by three questions involving decimals and fractions. Then the next question is about square roots. This way, you are preparing for any type of arithmetic question that you could encounter on the real exam. This helps you to be prepared for whatever questions the College Board/ETS throws yoiu way. Each chapter begins with an information and instruction overview describing the mathematical concepts covered in that particular section. Then you are presented with a variety of problems awaiting your solutions. [Pg.158]

This book helps to choose a path on the basis of an idea, fully described in the chapters, about how one can use the compounding requirements for polymer processing with a much greater understanding and broader approach, as well as providing an overview of compounding ingredients. [Pg.138]

It is much easier to learn chemistry if one already knows some chemistry That is, in order to go into any detail on any chemical topic, it is extremely helpful to have some very rudimentary knowledge of chemistry as a whole. For example, a crucial part of chemistry is an understanding of the nature of chemical compounds, the chemical formulas used to describe them, and die chemical bonds that hold them together these are topics addressed in Chapter 4 of this book. However, to understand these concepts, it is very helpful to know some things about the chemical reactions by which chemical compounds are formed, as addressed in Chapter 5. To work around this problem. Chapter 1 provides a highly condensed, simplified, but meaningful overview of chemistry to give the reader the essential concepts and terms required to understand more advanced chemical materiaL... [Pg.5]

Root, Michael. The TAB Battery Book An In-Depth Guide to Construction, Design, and Use. New York McGraw-HiU, 2011. Although this books requires some knowledge of chemistry and mathematics to appreciate fully, the introductory chapters about the history and basics of batteries provides a clear overview. [Pg.658]


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