ABC transporter gene

Ito, S., Ieiri, I., Tanabe, M., Suzuki, A., Higuchi, S., Otsubo, K., Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/ cMOAT, in healthy Japanese subjects, Pharmacogenetics 2001, 33, 175-184. 

Katiyar, S. K., Edlind, T. D., Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei, Med. Mycol. 2001, 39, 109-116. 

Ito S, Ieiri I, Tanabe M, Suzuki A, Higuchi S, Otsubo K. Polymorphism of the ABC transporter genes, MDR1,... 

For other efflux transporters such as BCRP (ABCG2), human pharmacokinetic and pharmacodynamic data are currently rare. However, an investigation of the influence of polymorphisms in ABC-transporter genes on the accumulation of nelfinavir in peripheral blood mononuclear cells (PBMCs) revealed no associations between the polymorphisms in the transporters analyzed and the accumulation of nelfinavir in the PBMCs [151], A second study in patients clearly demonstrated an increase in the AUC of the orally and intravenously administered BCRP substrate topotecan when it is given with GF120918, an inhibitor of P-glycoprotein and BCRP [152],... 

Szakacs G, Annereau JP, Lababidi S et al. Predicting drug sensitivity and resistance profiling ABC transporter genes in cancer cells. Cancer Cell 2004 6 129-137. 

Miyake K, Mickley L, Litman T, et al. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells demonstration of homology to ABC transport genes. Cancer Res 1999 59(1) 8 13. 

Phenylpyrroles fludioxonil Protein kinase (in glycerol synthesis) 4 Protein kinase (os 2) and ABC transporter gene (BcatrB) ... 

Szakacs G, Annereau JP, Lababidi S, Shankavaram U, Arciello A, Bussey KJ, Reinhold W, Guo Y, Kruh GD, Reimers M, Weinstein JN, Gottesman MM. Predicting drug sensitivity and resistance Profiling ABC transporter genes in cancer cells. Cancer Cell 2004 6 105-7. (Comment in Cancer Cell 2004 6 129-37.)... 

Franz, R., Michel, S., and Morschhauser, J. (1998) A fourth gene from the Candida albicans CDR family of ABC transporters. Gene, 220, 91-98. 

DeMicheli, M., Bille, J., and Sanglard, D. (1999) Regulation of ATP-binding cassette (ABC) transporter genes in Candida albicans. Presented at the ASM Conference on Candida and Candidiasis, Charleston, SC. 

Cervelatti, E.P., Fachin, A.L., Ferreira-Nozawa, M.S., and Martinez-Rossi, N.M. (2006) Molecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrum. Medical Mycology, 44, 141-147. 

Pearson, L.A. et al.. Inactivation of an ABC transporter gene, ntcyH, results in loss of microcystin production in the cyanobacterium Microcystis aeruginosa PCC 7806, Appl Environ. Microbiol, 70, 6370, 2004. 

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