Aarons

C. Parkaiiyi, J.-J. Aaron, Theoretical Organic Chemistry C. Parkanyi, Ed., 233, Elsevier, Amsterdam (1998). 

Can any number of identical subunits be accommodated in the asymmetric unit while preserving specificity of interactions within an icosahedral arrangement This question was answered by Don Caspar then at Children s Hospital, Boston, and Aaron Klug in Cambridge, England, who showed in a classical paper in 1962 that only certain multiples (1, 3, 4, 7...) of 60 subunits are likely to occur. They called these multiples triangulation numbers, T. Icosahedral virus structures are frequently referred to in terms of their trian-gulation numbers a T = 3 virus structure therefore implies that the number of subunits in the icosahedral shell is 3 x 60 = 180. 

This book is primarily directed at professional materials scientists and engineers, and they have no urgent need to see themselves defined. Indeed, it would be perfectly reasonable to say about materials science what Aaron Katchalsky used to say about his new discipline, biophysics Biophysics is like my wife. I know her, but I cannot define her (Markl 1998). Nevertheless, in this preliminary canter through the early history of MSE, it is instructive to examine briefly how various eminent practitioners have perceived their changing domain. 

Richard M. Breyer, Aaron N. Hata, Matthew D. Breyer... 

Aaron N. Hata Division of Nephrology Medical Center, Vanderbilt University Nashville, TN,... 

James P. Lodge John L. Margrave Leon Petrakis F. Sherwood Rowland Alan C. Sartorelli Raymond B. Seymour Aaron Wold Gunter Zweig... 

Aaron CK, Howland, MA. 1998. Insecticides Organophosphates and carbamates. In Goldfrank LR, Flomenbaum NE, Lewin NA, et al., eds. Goldfiank s toxicologic emergencies. Stamford, CT Appleton Lange, 1429-1449. 

Following inhibition by methyl parathion, acetylcholinesterase activity recovers as a result of the synthesis of new enzyme, generally at a rate of approximately 1% per day. However, the symptoms of methyl parathion poisoning usually resolve much more rapidly. Therefore, even though they are symptom-free, persons poisoned by methyl parathion may be hypersusceptible to its effects and should avoid reexposure for several weeks (Aaron and Howland 1998 Proctor et al. 1988). 

Methods of Reducing Toxic Effects. There is good information on the procedures used to limit absorption and to interfere with the mechanism of action of methyl parathion after acute exposures (Aaron and Howland 1998 Bronstein and Currance 1988 EPA 1989b Proctor et al. 1988 Stutz and Janusz 1988). However, no information is available on dealing with long-term, low-level exposures. 

Aaron, B.B. and Gosline, J.M., Elastin as a random-network elastomer A mechanical and optical analysis of single elastin fibers. Biopolymers, 20, 1247-1260, 1980. 

Bernard D. Blaustein Paul N. Craig Ellis K. Fields Louis Lykken Egon Matijevic Thomas J. Murphy Robert W. Parry Aaron A. Rosen Charles N. Satterfield... 

Nestorov lA, Aarons LJ, Rowland M. Physiologically based pharmacokinetic modeling of a homologous series of barbiturates in the rat a sensitivity analysis. / Pharmacokinet Biopharm 1997 25 413-47. 

Nestorov lA, Aarons LJ, Arundel PA, Rowland M. Lumping of whole-body physiologically based pharmacokinetic models. JPharmacokinet Biopharm 1998 Feb 26(l) 21-46. 

Blakey GE, Nestorov lA, Arundel PA, Aarons LJ, Rowland M. Quantitative structure-pharmacokinetics relationships I. Development of a whole-body physiologically based model to characterize changes in pharmacokinetics across a homologous series of barbiturates in the rat. J Pharmacokinet Biopharm 1997 Jun 25(3) 277-312. Erratum in J Pharmacokinet Biopharm 1998 Feb 26(l) 131. 

Kenneth B. Bischoff Ellis K. Fields Jeremiah P. Freeman E. Desmond Goddard Jesse C H. Hwa Philip C Kearney John L. Margrave Nina I. McClelland John B. PfeiflFer Joseph V. Rodricks Roy L. Whistler Aaron Wold... 

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