2H-l-Benzopyran-2-one

Coum rinic Acid Compounds. These synthetic phyUoquinone derivatives and congeners have been employed as anticoagulants since the isolation of 3,3 -methylenebis(4-hydroxy-2H-l-benzopyran-2-one) [66-76-2] (bis-4-hydroxycoumarin or dicoumarol) (1) from spoiled sweet clover in 1939. The ingestion of the latter was responsible for widespread and extensive death of bovine animals at that time. The parent compound for the synthesis of many congeners is 4-hydrocoumarin, which is synthesized from methyl salicylate by acetylation and internal cyclization. The basic stmctures of these compounds are shown in Figure 2, and their properties Hsted in Table 6 (see Coumarin). 

H-l-Benzopyran-2-ones — see Coumarins Benzopyran-4-ones ring atoms... 

C H,jN 555S-29-2) see Isoaminile 6-methyl-4-phenyl-3,4-dihydro-2H-l-benzopyran-2-one (C (jH 402 40546-94-9) see Tolterodine... 

Ayyangar NR, Srinivasan KV, Daniel T (1991) Polycyclic compounds Part VII. Synthesis, laser characteristics and dyeing behaviour of 7-diethylamino-2H-l-benzopyran-2-ones. Dyes Pigm 16 197-204... 

In contrast to the benzoannelated nitrogen heterocycles, only a few kinds of benzoannelated systems without nitrogen have been described (Fig. 3.15). Five-mem-bered rings such as benzo[b]furans (336) [184, 461] and hydrobenzo[b]furans (337) (Scheme 3.41) [337, 462, 463] and six-membered rings like 4H-l-benzopyran-4-ones (4-chromones) (338) and 2H-l-benzopyran-2-ones (coumarines) (339) [96, 464, 465] 2,3-dihydro-4H-l-benzopyran-4-ones (chroman-4-ones) (340) [466] and 3,4-dihydro-lH-2-benzopyrans (isochromans) (341) [444] have been reported. 

Coumarin (2H-l-benzopyran-2-one) is a known inhibitor of cellulose formation,355-357 and Hopp and coworkers358 found that, in membranes from the alga Prototheca zopfii, it inhibits the transfer in vitro of the lipid-linked cello-oligosaccharide to its protein acceptor (see Section II,2,b). 

Coumarins (also called 2H-l-benzopyran-2-ones or 2-oxo-2H-chromenes) are common in nature and find their main applications as fragrances, pharmaceuticals and... 

H-l-Benzopyran-2-ones — see Coumarins Benzopyran-4-ones ring atoms reactivity, 3, 692-706 substituents reactivity, 3, 707-718... 

Chemical Name 3-[3-(4-Chlorophenyl)-l-(5-chloro-2-thienyl)-3-hydroxypropyl]-4-hydroxy-2H-l-benzopyran-2-one... 

In the present study, we describe the effects produced by 3-formyl-chromones substituted at the 6-position. We evaluated their cytotoxicity against human tumor cell fines and normal cells, and also investigated the structurally related coumarine (2H- l-benzopyran-2-one) derivatives [24]. 

Benzoxazole 2,1 Benzisoxazole Naphthalene 1,2,3,4-Tetra- Octahydronaphthalene 2H-l-Benzopyran 2H-l-Benzopyran-2-one... 

SYNS 3-(o-ACETONYLBENZYL)-4-HYDROXY-COUMARIN SODIUM SALT ATHROMBIN COUMADIN SODIUM 4-HYDROXY-3-(3-OXO-l-PHENYLBUTYL)-2H-l-BENZOPYRAN-2-ONE SODIUM SALT (9CI) MAREVAN (SODIUM SALT) ... 

G.16) 2//-l-Benzopyran-2-one, 7-hydroxy-6-methoxy-, 7-hydroxy-6-methoxy-2W-chromen-2-one. 7-hydroxy-6-methoxy-2H-l-benzopyran-2-one, 7-hydroxy-6-methoxycoumarin, scopoletin, 0-methylesculetin 92-61-5 ... 

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