Zinc finger encoding genes

Fortini, M. E., Lai, Z., and Rubin, G. M. (1991). The Drosophila zfli-1 and zfli-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs. Mech. Dev. 34 113-122. 

Hashimoto, T., Nakano, Y., Morinaga, T., and Tamaoki, T. (1992). A new family of homeobox genes encoding multiple homeodomain and zinc finger motifs. Mech. Dev. 39 125-126. 

Levitan DJ, BoydL, Mello CC, Kemphues KJ, Stinchcomb DT 1994par-2, a gene required for blastomere asymmetry in Caenorhahditis elegans, encodes zinc-finger and ATP-binding motifs. Proc Natl Acad Sci USA 91 6108-6112... 

The lack of zinc can also be a problem in biological systems and is responsible for disease states. For example, nitric oxide-dependent apoptosis can be induced in motor neurons by zinc-deficient SOD, and in some cases of amyotrophic lateral sclerosis, zinc-deficient SOD may participate in this type of oxidative mechanism involving nitric oxide.969 One form of hereditary human hair loss or alopecia was mapped to a specific gene and a mutation found in affected individuals. The gene encodes a single zinc finger transcription factor protein with restricted expression in the brain and skin.970 Zinc has been implicated in Alzheimer s via beta amyloid formation, and a role has been attributed for the cerebral zinc metabolism in the neuropathogenesis of Alzheimer s disease.971... 

Prakash, The Sacdiaromyces cerevisiae RAD 18 gene encodes a protein that contains potential zinc finger domains for nudeic acid binding and a putative nudeotide binding sequence. Nucleic Acids Res, 1988, 16(14B), 7119-31. 

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