ZENECA Agrochemicals

Zeneca Agrochemicals, Jealott s Hill Research Station, Bracknell, Berkshire, RG42 6ET... 

Robin Taylor Zeneca Agrochemicals Jealott s Hill Research Station Bracknell, Berkshire, RG12 6EY England... 

Picoxystrobin was developed by Zeneca Agrochemicals (now Syngenta AG) and first registered in 2001. Picoxystrobin is prepared as shown in Scheme 11.7. Coupling the 2-hydroxypyridine 24 with corresponding benzyl chloride 25 under phase-transfer conditions followed by introduction of the methoxymethylene moiety yields picoxystrobin. The introduction of the trifluoromethyl group of 24 is achieved by chlorination of 2-picoline (23) followed by fluorination using HF and hydrolysis. 

Trade Name Synonyms Anvil [Zeneca Agrochems. http //www.zenecaag.com]... 

Zeneca Agrochemicals/Zeneca Crop Protection, Part of AstraZeneca, Fernhurst, Haslemere, Surrey, GU27 3JE, UK (Tel 44 1428 657 222 FAX 44 1428 657 385 Internet http //www.zenecaag. com)... 

Girard N Tadros T F Bailey AI Zeneca Agrochemicals Imperial College... 

R. Blattner, Industrial Research Limited, Lower Hutt, New Zealand K. Clinch, Zeneca Agrochemicals, Bracknell, Berks. 

We wish to thank our many colleagues at ZENECA Agrochemicals who have participated in this project, particularly Vivienne Anthony, Brian Baldwin, David Bartlett, Ian Streeting and Tom Wiggins. 

National Research Council of Canada, 25 North Carolina State University, 172 Research and Development Corporation of Japan (JRDC), 162 Ruhr-Universitat Bochum, 449 Sandoz Agro Ltd., 25 Sankyo Company, Ltd., 74 The Scripps Research Institute, 230 Stine-Haskell Research Center, 407 Texas A M University, 210 U.S. Department of Agriculture, 2,85,172, 182,210,268,292,320,324,474,497 University of Arkansas, 384 University of California—Berkeley, 130,336 University of California— Davis, 348,368 University of California— Riverside, 249 University of Nottingham, 259 Virginia Commonwealth University, 230 ZENECA Agrochemicals, 37... 

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