Zataria multiflora

Shoeibi, S., N. Rahimifard, B. Pirouz, et al. 2009. Mutagenicity of four natural flavors Clove, cinnamon, thyme and Zataria multiflora Boiss. ). Med. Plant 8 (Suppl. 5) 89-96. 

Zomorodian, K., Saharkhiz, M. J., Rahimi, M. J., Bandegi, A., Shekarkhar, G., Bandegani, A. et al. Oanuary-March 2011). Chemical composition and antimicrobial activities of the essential oils from three eco types of Zataria multiflora. 7(25), 53-59. 

Karimian. R. G. Kavoosi, and M.J. Saharkhiz, 2012. Antioxidant, nitric oxide scavenging and malondialde-hyde scavenging activities of essential oils from different chemotypes of Zataria multiflora. Nat. Prod. Res.. 26(22) 2144-2147. 

Kavoosi, G. and J.A. Teixeira da Silva, 2012. Inhibitory effects of Zataria multiflora essential oil and its main components on nitric oxide and hydrogen peroxide production in glucose-stimulated human monocytes. 

Saei Dehkordi, S.S., H. Tajik, M. Moradi, and F. Khalighi Sigaroodi, 2010. Chemical composition of essential oils in Zataria multiflora Boiss. from different parts of Iran and their radical scavenging and antimicrobial activity. Food Chem. Toxicol.. 48(6) 1562 1567. 

Shari far, F., A. Derakhshanfar, G. Dehghan Nndeh et al., 2012. In vivo antioxidant activity of Zataria multiflora Boiss essential oils. Pak. J. Pharm. ScL, 24(2) 221 225. 

Khosravi, A. R., Eslami, A. R., Shokri, H., Kashanian. M. 2008. Zataria multiflora cream for the treatment of acute vaginal candidiasis. 101 201-202. 

Mahmoudabadi, A. Z., Dabbagh, M. A., Fouladi, Z. 2006. In vitro anti-candida activity of Zataria multiflora Boiss. Evid. Based Comvlement. Alternat Med. 4 351-353. 

Mansoori, R, Hadjiakhondi, A., Ghavami, R., Sha ee, A. 2002. Clinical evaluation of Zataria multiflora essential oil mouthwash in the management of recurrent aphthous stomatitis. Daru 10 74-77. 

Zataria multiflora Boiss. Lamiaceae Carvacrol, linalool, a-pinene, p-( mene Saharkhiz et al. (2010)... 

Two different ecotypes of Zataria multiflora Boiss, Lamiaceae, were tested in the study conducted by Saharkhiz et al. (2010). Ecotype B had similar constituents but in lower concentrations this also explains why ecotype A was more successful in inhibiting the germination and growth of the tested weeds, which were Hordeum spontaneum Koch, Secale cereale, A. retroflexus, and Cynodon dactylon. 

Saharkhiz, M. J., S. Smaeili, and M. Merikhi, 2010. Essential oil analysis and phytotoxic activity of two ecotypes of Zataria multiflora Boiss. growing in Iran. 24 1598-1609. 

FIGURE 9.1 Antinociceptive activity of Zataria multiflora in tail-flick test in rats. 

In a double-blind, randomized study, 60 patients with RAS received either 30 mL of an oral mouthwash composed of 60 mg of Zataria multiflora essential oil in an aqueous-alcoholic solution or placebo thrice daily for 4 weeks. In the treatment group, 83% of patients responded well while 17% reported a deterioration of their condition. This was compared with 13% and 87% for the placebo group, respectively. A significant clinical improvement with regard to less pain and shorter duration of the condition was found in the essential oil group (Mansoori et al., 2002). 

Carvacrol elicits an inhibitory effect on histamine receptors, as Boskabady et al. [95] report. They examined the effect of an aqueous-ethanoUc extract of Zataria multiflora Boiss (Labiatae) and its constituent carvacrol on HI (histamine 1) receptors in tracheal chains of guinea pigs. The results crmfirmed the inhibitory effect of both extract and carvacrol on HI receptors with no significant difference when different concentrations of extract and carvacrol where applied. 

Boskabady MH, Tabanfar H, Gholamnezhad Z, Sadeghnia HR (2011) Inhibitory effect of Zataria multiflora Boiss and carvacrol on histamine (H(l) ) receptors of guinea-pig tracheal chains. Fundam Clin Pharmacol. doi 10.1111/j.l472-8206.2011.00971.x... 

Sharififar, F., M. H. Moshafi, S. H. Mansouri, M. Khodashenas, and M. Khoshnoodi. 2007. In vitro evaluation of antibacterial and antioxidant activities of the essential oil and methanol extract of endemic Zataria multiflora Boiss. Food Control 18(7) 800-805. 

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