Zanardi

G. Rassu, E. Zanardi, L. Battistini, andG. Casiraghi, Synlett, 1333 (1999). 

Podewils, L. J., Zanardi Blevins, L., Hagenbuch, M., Itani, D., Burns, A., Otto, C., Blanton, L., Adams, S., Monroe, S. S., Beach, M. J., and Widdowson, M. (2007). Outbreak of norovirus illness associated with a swimming pool. Epidemiol. Infect. 135, 827-833. 

Smeraldi, E., Zanardi, R. et al. (1998). Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol. Psychiatry, 3(6), 508-11. Wang, S. L., Huang, J. D. et al. (1993). Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects polymorphism in RFLP and DNA sequence of CYP2D6. Clin. Pharmacol. Ther., 53(4), 410-18. 

Zanardi, R., Serretti, A. etal. (2001). Factors affecting fluvoxamine antidepressant activity influence of pindolol and 5-HTTLPR in delusional and nondelusional depression. Biol. Psychiatry, 50(5), 323-30. 

Zanardi, R. et al. (2000). Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. /. Clin. Psychopharmacol., 20(1), 105-7. 

The most interesting aspect of the results of the study by Lee etal (2004) is that they also differ from those in a Caucasian population (Smeraldi, Benedetti Zanardi, 2002). The authors reported a more favorable natural history in those with the s/s genotype than in 1-allele carriers, which also differs from acute antidepressant responses in Caucasian populations. The frequencies of the s and 1 alleles among the Korean sample were approximately 86% and 14%, respectively, while the corresponding figures for Caucasians are 43% and 57% (Lesch etal, 1996). 

Cusin, C., Serretti, A., Zanardi, R. etal. (2002). Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity. Int.. Neuropsychopharmacol, 5, 27-35. 

Smeraldi, E., Zanardi, R. Benedetti, F. (1998). Polymorphism within the promoter of the serotonin transporter gene and antidepressants efficacy of fluvoxamine. Mol. Psychiatry, 3,508-11. 

Smeraldi, E., Benedetti, F. Zanardi, R. (2002). Serotonin transporter promoter genotype and illness recurrence in mood disorders. Eur. Neuropsychopharmacol. 12, 73-5. 

It has been shown by Zanardi, Nanni and coworkers that, instead of isocyanides, isothiocyanates can be used in the radical process [90]. Treatment of the mixture of the diazonium tetrafluoroborates 3-217 and the isothiocyanates 3-218 with pyridine or a mixture of 18-crown-6 and potassium acetate in ethyl acetate, furnished the benzothienoquinoline derivatives 3-219. In addition, in some cases the rearranged products 3-220 were furnished in low to reasonable yields (Scheme 3.57). 

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