3,5-Xylenol methyl ether

Not only anisole and methyl anisoles but also cresols and xylenols are formed. In a typical experiment, a product composition, in mol%, is 37.3% unreacted phenol, 37.2% anisole, 9.7% methyl anisoles, 1% dimethyl anisoles, 10.4% cresols and 4.4% xylenols. The C-methylated products were shown to occur via fast initial 0-methylation of the phenol followed by an inter-molecular rearrangement of the aryl methyl ethers to methyl phenols (28). 

Now let us consider the separation of 2,6-xylenol// -cresol mixtures. Here, the situation is reversed. The distribution coefficient of 2,6-xylenol (pAf = 10.62) is higher than that of /j-cresol (pATg = 10.28) because of the close proximity of the two methyl groups to the hydroxyl group. For such a mixture, the use of a polar solvent will be detrimental because a free -OH group on / -cresol can interact with polar solvents. Thus an inert solvent is a better choice. Indeed, separation factors are about 6 in dibutyl ether, 13 in benzene, and 35 in n-heptane (Gaikar and Sharma, 1985). 

Dimethylamine Dimethyl formamide Dimethylolpropionic acid 2,2-Dimethylpropanol Diphenylamine Ethylene chlorohydrin Hydrogen cyanide Hydroquinone monomethyl ether Isoquinoline Methyl isocyanate Nonanoic acid Phenolsulfonic acid Phosphorus oxychloride Pyrrole Quinaldine Sodium nitrate Stannic chloride Strontium salicylate Thioglycolic acid o-Xylene 2,3-Xylenol 2,3-Xylidine pharmaceutical mfg., orals Candelilla (Euphorbia cerifera) wax Cholecalciferol Ergocalciferol pharmaceutical mfg., parenterals Cholecalciferol Ergocalciferol pharmaceutical processing Chlorotrifluoromethane pharmaceutical prods. 

Methyl benzoate Phenyl acetate Phenethyl alcohol 2,4-Xylenol m-Dimethoxybenzene Veratrole Dimethylaniline Ethylaniline Ethyl fumarate Ethyl maleate 2-Ethylcaproic acid Isoamyl lactate Octyl alcohol cc-Octyl alcohol Bis(2-ethoxyethyl) ether Indene... 

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