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Wnt/B-catenin

Androgen-independent prostate cancer cell lines exhibit high levels of Wnt/B-catenin signaling. The non-steroidal anti-inflammatory dmg, sulindac sulfide, celecoxib, the cyclooxygenase-2 inhibitor, the nitric oxide-donor aspirin-derivative. [Pg.80]

Phihpp 1, Aufschnaiter R, Ozbek S, Pontasch S, Jenewein M, Watanaba H, Rentzsch F, Holstein TW, Hobmayer B. Wnt/B-catenin and noncanonical Wnt signaling interact in tissue evagination in the simple eumetazoan Hydra. Proc Natl Acad Sci USA. 2009 106 4290-5. [Pg.656]

Choi HY, Lim JE, Hong JH. Cureumin interrupts the interaction between the androgen receptor and Wnt/B-catenin signaling pathway in LNCaP prostate cancer cells. Prostate Cancer Prostatic Dis. 2010 13 3493-349. [Pg.657]

Lu W, Tinsley HN, Keeton A, Qu Z, Piazza GA, Li Y. Suppression of Wnt/B-catenin signahng inhibits prostate cancer cell proliferation. Eur J Pharmacol. 2009 602 8-14. [Pg.657]

Agathocleous M, lordanova 1, Willardson MI, Xue XY, Vetter ML, Harris WA, Mootre KB. A directional Wnt/B-catenin Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development... [Pg.657]

BETA-CATENiN This protein is an 88 kD member of the catenin family of proteins that are important constituents of the cytoskeleton. Beta-catenin is also important in gene expression and is a member of the Wnt signaling cascade. In certain conditions, when the normal degradation of B-catenin is disrupted, this protein accumulates in the cytoplasm and abnormally translocates to the nucleus where it can disrupt normal gene expression. ... [Pg.500]

Arnold, S. J., Stappert, J., Bauer, A., Kispert, A., Herrmann, B.G., Kemler, R. 2000. Brachyury is a target gene of the Wnt/beta-catenin signaling pathway. Mech. Dev. 91, 249-258. [Pg.96]

Lickert, H., Domon, C., Huls, G., Wehrle, C., Duluc, I., Clevers, H., Meyer, B.I., Freund, J.N., Kemler, R. 2000. Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdxl in embryonic intestine. Development 127, 3805-3813. [Pg.101]

Cselenyi CS, Jemigan KK, Tahinci E, Thome CA, Lee LA, Lee E. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3 s phosphorylation of B-catenin. Proc Natl Acad Sci USA. 2008 105 8032-7. [Pg.656]

Stanczak A, Stec R, Bodnar 1, Olszewski W, Cichowicz M, Kozlowski W, Szczylik C, Pietrucha T, Wieczorek M, Lamparska-Przybysz M. Prognostic significance of Wnt-1. B-catenin and E-cadherin expression in advaneed colorectal carcinoma. Pathol Oncol Res. 2011 17 955-63. [Pg.656]

Wang Y, Fu Y, Gao L, Zhu G, Liang J, Gao C, Huang B, Fenger U, Niehrs C, Chen YG, Wu W. Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. J Biol Chem. 2010 285 10890-901. [Pg.694]

Moon RT, Bowerman B, Boutros M et al (2002) The promise and perils of Wnt signaling through beta-catenin. Science 296 1644-1646... [Pg.304]

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See also in sourсe #XX -- [ Pg.25 , Pg.123 , Pg.415 , Pg.536 , Pg.537 , Pg.538 , Pg.569 , Pg.572 ]



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