Wine yeast genomic analysis

Backhus, L. E., DeRisi, J., Brown, P. O., Bisson, L. E. (2001) Eunctional genomic analysis of a commerdal wine strain of Saccharomyces cerevisiae under differing nitrogen conditions. FEMS Yeast Research, 1, 111-125... 

There are two main goals for the genomic analysis of wine yeast. The first... 

One of the major areas of research interest in wine strains of S. cerevisiae is the analysis of response to stress. This focus is motivated by both practical and fimdamental interests. The production of wine imposes both biotic and abiotic stresses on the yeast. The principal stresses encountered are high osmolarity, high ethanol, extremes of temperature, nutrient limitation, and presence of inhibitory metabolites (Bisson, 1999). Genomic analysis of the response to each of these types of stress has been conducted (Alexandre et al., 2001 Aranda and del Olmo, 2004 Backhus et al., 2001 Erasmus et al., 2003 Kuhn et al., 2001 Marks et al., 2003 Rep et al., 2000 Rossignol et al., 2006 Sahara et al., 2002). Several... 

Rossignol, T., Postaire, O., Storai, J., and Blondin, B. 2006. Analysis of the genomic response of a wine yeast to rehydration and inoculation. Appl. Microbiol. Biotechnol. 71, 699-712. 

Borneman, A. R., Forgan, A. H., Pretorius, I. S., Chambers, P. J. (2008). Comparative genome analysis of a Saccharomyces cerevisiae wine strain. FEMS Yeast Research, 8,1185-1195. 

In the late 1980s, owing to the development of genetics, certain techniques of molecular biology were successfully applied to characterize wine yeast strains. They are based on the clonal polymorphism of the mitochondrial and genomic DNA of S. cerevisiae. These genetic methods are independent of the physiological state of the yeast, unlike the previous techniques based on the analysis of metabolism byproducts. 

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