Whittle laboratory

I must express my appreciation to many colleagues in the Whittle Laboratory of the Engineering Department at Cambridge University. In particular I am grateful to Professor John Young who readily made available to me his computer code for real gas cycle calculations and to Professors Cumpsty and Denton for their kindness in extending to me the hospitality of the Whittle Laboratory after I retired as Vice-Chancellor of the Open University. It is a stimulating academic environment. 

During the course of this work, which was carried out at the Whittle Laboratory, University of Cambridge, A. Guha was supported by a Nehru Scholarship. ... 

Mr. A. Guha Whittle Laboratory Madingley Road Cambridge CB3 OHE England... 

I first became interested in the subject of cycles when I went on sabbatical leave to MIT, from Cambridge England to Cambridge Mass. There I was asked by the Director of the Gas Turbine Laboratory, Professor E.S.Taylor, to take over his class on gas turbine cycles for the year. The established text for this course consisted of a beautiful set of notes on cycles by Professor (Sir) William Hawthorne, who had been a member of Whittle s team. Hawthorne s notes remain the best starting point for the subject and I have called upon them here, particularly in the early part of Chapter 3. 

Whittle [29] has described a thin-layer chromatographic method for the identification of hydrocarbon marker dyes in oil polluted waters. McLeod et al. [25] conducted interlaboratory comparisons of methods for determining traces of aliphatic and aromatic hydrocarbons in marine sediments. Agreement within a factor of 2 to 3 was obtained between the 12 participating laboratories. 

Effect of the extracts on the increased vascular permeability induced by acetic acid in mice was determined according to Whittle method with some modifications [5]. Each test sample was administered orally to a group of ten mice, which were male Swiss albino mice (20-25 g) were purchased from the animal breeding laboratories of Refik Saydam Central Institute of Health (Ankara, Turkey), in 0.2 mF20 g body weight. Thirty minutes after the administration each mice was injected with 0.1 ml of 4% Evans blue (Sigma, St. Louis, Missouri, USA) in saline solution (/.v.) at the... 

Charles,432 working in Whittle s laboratory, photolyzed CF3COCF3 in the presence of NO and found CF3NO and CO as sole products in the ratio of 2 to 1. Assuming Ayscough s15 value of 2 x 1010 M l sec-1 for the CF3 recombination-rate constant, he concluded that kis > 10s M-1 sec-1 at 25°C. 

The second author (RML) would like to record his indebtedness to Professor K. J. Whittle for access to computer services at The Tony Research Station, Aberdeen, in its last days, and to Professor A.D. Hawkins for use of the library facilities at the Marine Laboratory, Aberdeen. Without such help this work could not have been completed. 

One of the virtues of spectroscopic approaches is that they are commonly nondestructive and noninvasive, although some procedures involve the attachment of labels chemically at specific sites. The former approaches are particularly valuable for in vivo studies. In laboratory experiments, the amounts of materials required range from the femtomole (10 mol) level for some particularly sensitive fluorescence approaches to milligrams or more for typical EPR, infrared, or X-ray spectroscopy. Ongoing requirements in instrumentation and techniques are continually whittling away at the limits to the amount of material required. 

Question by H. R. Whittle, UKAEA Culham Laboratory Would you please comment upon the amount of glass in your sealants ... 

Weil CS, Scala A (1971) Study of intra- and inter-laboratory variability in the results of rabbit eye and skin irritation tests. Toxicol Appl Pharmacol 19 276-360 Whittle E, Barratt MD, Carter JA, Basketter DA, Chamberlain M (1996) Use of QSAR and an in vitro skin corrosivity test to investigate the corrosion/irritation potential of organic acids. Toxicol In Vitro 10 95-100... 

John Shanklin, Edward J. Whittle, and Brian G. Fox" Dept of Biology, Brookhaven National Laboratory, Upton, NY 11973 USA and Enzyme Institute, University of Wisconsin-Madison, Madison, WI 53705... 

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