What to Submit

Presently, it is assumed that all submissions of sequences are done electronically via the World Wide Web, by electronic mail, or (at the very least) on a computer disk sent via regular postal mail. The URLs and E-mail addresses for electronic submissions are shown in the list at the end of the chapter. 

The submission process is quite simple, but care must be taken to provide information that is accurate (free of errors and vector or mitochondrial contamination) and as biologically sound as possible, to ensure maximal usability by the scientific community. Here are a few matters to consider before starting a submission, regardless of its form. 

Is the Sequence Synthetic, But Not Artificial There is a special division 

How Accurate is the Sequence This question is poorly documented in the database literature, but the assumption that the submitted sequence is as accurate as possible usually means at least two-pass coverage (in opposite orientations) on the whole submitted sequence. Equally important is the verification of the final submitted sequence. It should be free of vector contamination (this can be verified with a BLASTN search against the VecScreen database see Chapter 8 and later in this 

A submission of nucleotide also means the inclusion of the protein sequences it encodes. This is important for two reasons  

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Spatial differentiation. The idea was borrowed from systems like SharedNotes [12] in which a specific region within a slide is defined as a public area and the rest of the slide is a private area. In our case, only notes within the public area (the area within the frame, see Fig. 4) may be shown on the public display. This design is intuitive and robusL but it prevents users from writing personal comments near pertinent information in the public area. Furthermore, users must determine a priori what to submit and what not to submif which is not compatible with the typical user experience. Thus we turn to pen-based strategies. 

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