Wells, Frank

Everly Schweinsberg Traynham 1. Am. Chem. Soc. 1978, 100, 1200 Wells Franke Tetrahedron Lett. 1979, 4681. 

There s one question you asked that I d like to answer namely about how a certain party of Corey s project is getting along. Well frankly, old boy, as well as could be expected, if you don t expect much. It still arises at 7 00 or shortly thereafter, works about 8 hrs., and comes home to a dull evening at home. 

When employees are not active participants in the safety program, involved in its design, ongoing implementation, and evaluation in some way, well, frankly... it s not their car. 

The reports were that water condensed from the vapor phase into 10-100-/im quartz or pyrex capillaries had physical properties distinctly different from those of bulk liquid water. Confirmations came from a variety of laboratories around the world (see the August 1971 issue of Journal of Colloid Interface Science), and it was proposed that a new phase of water had been found many called this water polywater rather than the original Deijaguin term, anomalous water. There were confirming theoretical calculations (see Refs. 121, 122) Eventually, however, it was determined that the micro-amoimts of water that could be isolated from small capillaries was always contaminated by salts and other impurities leached from the walls. The nonexistence of anomalous or poly water as a new, pure phase of water was acknowledged in 1974 by Deijaguin and co-workers [123]. There is a mass of fascinating anecdotal history omitted here for lack of space but told very well by Frank [124]. 

Fig. 3.12. Schematic growth rate plot showing regimes with sharp breaks in slope, as well as the smooth transition predicted by the Frank model...

Cuello was excavated by Hammond and co-workers between 1975 and 1993. It is the earliest known Preclassic Maya site, with a Preclassic occupation from ca. 1200 BC to AD 300 as well as later Classic period (AD 300-900) remains the earliest pottery-using phase (Swasey, 1200-900 BC) has not yet been found at other Preclassic sites, but the Bladen (900-600 BC) and subsequent phases match occupations elsewhere in date and material culture. The Cuello excavations have been extensively described in the report edited by Hammond (1991). Of particular relevance here are the chapters on the ecology and subsistence economy (Ch. 4) by Miksicek and by Wing and Scudder, and on the human burials (Ch. 7), by Frank and Julie Saul. More recent publications have focused on the subsistence economy (Crane and Carr 1994) and on the human skeletal remains (Saul and Saul 1997). 

Most of the actual reactions involve a three-phase process gas, liquid, and solid catalysts are present. Internal and external mass transfer limitations in porous catalyst layers play a central role in three-phase processes. The governing phenomena are well known since the days of Thiele [43] and Frank-Kamenetskii [44], but transport phenomena coupled to chemical reactions are not frequently used for complex organic systems, but simple - often too simple - tests based on the use of first-order Thiele modulus and Biot number are used. Instead, complete numerical simulations are preferable to reveal the role of mass and heat transfer at the phase boundaries and inside the porous catalyst particles. 

To answer this question we need to consider the kind of physical techniques that are used to study the solid state. The main ones are based on diffraction, which may be of electrons, neutrons or X-rays (Moore, 1972 Franks, 1983). In all cases exposure of a crystalline solid to a beam of the particular type gives rise to a well-defined diffraction pattern, which by appropriate mathematical techniques can be interpreted to give information about the structure of the solid. When a liquid such as water is exposed to X-rays, electrons or neutrons, diffraction patterns are produced, though they have much less regularity and detail it is also more difficult to interpret them than for solids. Such results are taken to show that liquids do, in fact, have some kind of long-range order which can justifiably be referred to as a structure . 

Oh, I hear Dame Elysabeth very well. The King turned so far toward me that I could not without frank discourtesy escape his eye. And see her, too. I m told Henry of Lancaster was wont to say that my good friend Rivers and the Duchess were the handsomest couple in his kingdom. I ought not to be surprised that they have sired the most beautiful children in mine, but still it astonishes me. Your brother Scales is a fine man too, and learned with it. My brother Antony Oh, sire, have you had word from him lately ... 

The SPOT-synthesis method also employs Fmoc chemistry but uses hydroxyl groups present on cellulose filter paper to derivatize and thereby immobilize (3-alanine groups onto the paper. After deprotection, the 13-alanine groups can be used as platforms for the synthesis of peptide arrays (Fig. 7.5) (Frank, 1992 Gausepohl et al., 1992). This method has been widely used for mapping antigen-antibody interactions as well as protein-DNA, protein-metal and other protein-protein interactions (Reineke et al., 2001). 

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