Voltage-gated anion-selective channel

Solutes enter mitochondria through pores in thousands of molecules of the voltage-gated anion-selective channel VDAC, also known as mitochondrial porin.1516 288 289 In the absence of a membrane potential these pores allow free diffusion to molecules up to 1.2 kDa in mass and may selectively permit passage of anions of 3- to 5-kDa mass. However, a membrane potential greater than 20 mV causes the pores to close. NADH also decreases permeability. 

Solutes enter mitochondria through pores in thousands of molecules of the voltage-gated anion-selective channel VDAC, also known as mitochondrial In the absence of a membrane... 

When comparing transmitter-gated ion channels on a functional level, one can discern between anion and cation channels. The former ones comprise the GABAa and glycine receptors, which display a rank order of anion selectivity of I- > Hr > Cl- and which are also permeable to HC()3. All other ionotropic receptors mentioned here are cation channels, which discriminate rather poorly between various monovalent cations, at least when compared with voltage-gated ion channels. Some... 

Leontidis E, Aroti A, Belloni L (2009) Liquid expanded monolayers of lipids as model systems to understand the anionic Hofmeister series 1. A tale of model. J Phys Chem B 113 1447-1459 Levitsky VY, Panova AA, Mozhaev VV (1994) Correlation of high-temperamre stability of a-chymotrypsin with salting-in properties of solution. Eur J Biochem 219 231-236 Lipkind GM, Fozzard HA (2008) Voltage-gated Na channel selectivity the role of the conserved domain III lysine residue. J Gen Physiol 131 523-529 Lo Nostro P Fratoni L, Ninham BW, Baglioni P (2002) Water absorbency by wool fibers Hofmeister effect. Biomacromolecules 3 1217-1224... 

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