Virus-ligand interactions

Rabbit hemorrhagic disease virus Rhinoviruses STD NMR Virus-ligand interaction... 

The ligand-based NMR studies on virus-ligand interactions published so far indicate that experimental conditions have to be chosen carefully, as described above. Once proper conditions are met, STD NMR lends itself especially well to systematic studies of ligand binding to viruses and VLPs. We are convinced that in the future the combination of ligand-based NMR experiments and X-ray crystallography will improve our understanding of viral entry mechanisms. 

Lipid Domains, Chemistry of Receptor Tyrosine Kinases Receptor-Ligand Interactions Receptors, Chemistry of Signal Transduction Across Membranes Virus-Based Drug Delivery... 

Virus-receptor interactions have also been shown to be affected by these ManN derivatives [154,155]. Treatment of human B-lymphoma BJA-B cells or African green monkey kidney epithelium cells with either ManProp, ManBut, or ManPent resulted in structural modification of about 50% of total cell surface sialic acids. Polyoma viruses, which use sialic acids as ligands for binding prior to infection, show either reduced or enhanced ability to infect cells carrying these modified sialic... 

---