Virulence extracellular

OH 0, v 0 A r-(3-hydroxybutyryl)-L-homoserine lactone, HBHL or 3-OH, C4-HSL Vibrio harveyi Xenorhabdus nematophilus Bioluminescence, polyhydroxybutyrate metabolism. Virulence, extracellular lipase. 

H 0 A-butanoyl-L-homoserine lactone, BHL or C4-HSL Aeromomas hydrophila Aeromonas salmonicida Pseudomonas aeruginosa, Serratia liquefaciens Extracellular protease, biofilm formation. Extracellular protease. Virulence factors - alkaline protease, cyanide, elastase, haemolysin, lectins, pyocyanin, rhaminolipid, RpoS Swarming, protease. 

Moser, M., Menz, G., Blaser, K., and Crameri, R. (1994). Recombinant expression and antigenic properties of a 32-kilodalton extracellular alkaline protease, representing a possible virulence factor from Aspergillus fumigatus. Infect. Immun. 62, 936-942. 

K.J. Kwon-Chung, D. Lehman, C. Good, and P.T. Magee, Genetic evidence for role of extracellular proteinase in virulence of Candida albicans, Infect. Immun., 49, 571, 1985. 

Bidochka, M. J., and Khachatourians, G. G. (1990). Identification of Beauveria bassiana extracellular protease as a virulence factor in pathogenicity toward the migratory grasshopper, Melanophis sanguinipes. Journal of Invertebrate Pathology, 56, 362-370. 

Bottcher T, Sieber SA (2008) P-Lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureus. J Am Chem Soc 130 14400-14401... 

Garcia Vescovi, E., Soncini, F.C., Groisman, E.A. Mg2+ as an extracellular signal environmental regulation of Salmonella virulence. Cell 84 (1996) 165-174. 

Some recent studies have indicated the involvement of the fsr system in virulence, which includes not only the effect of the induced extracellular proteases but also the effect of expression of other genes controlled by fsr system.195,201-203 It was also demonstrated that fsr system is involved in biofilm formation of E. faecalis cells.204,205... 

Capsular and extracellular polysaccharides are involved in several aspects of cellular behavior that are tied to bacterial survival and virulence [321]. The capsule layer provides a physical barrier that prevents the bacteria from drying out, aiding in survival outside a host. CPS are also involved in colonization and biofilm formation. In some bacteria CPS promote adherence to surfaces, aiding colonization and biofilm formation, while CPS in other bacteria inhibit adhesion and biofilm formation [344]. 

---