Vigabatrin

C32H44N2O21 143436-67-3) see Docarpamine l,l-bis(ethoxycarbonyl)-2-vinylcyclopropane (C, H 04 7686-78-4) see Vigabatrin 3,3 20 0-bis(ethylenedioxy)-lip,17 1-trihydroxy-5-preg-nene... [Pg.2309]

Vigabatrin (not marketed in United States), tiagabine, topiramate, gabapentin, carbamazepine, lamotrigine... [Pg.195]

Vigabatrin has an unacceptable adverse effect profile, but consistent findings in animal studies suggest that GABA agonists deserve further study. a-AMPA antagonism, or antikindling action, may also be important for some anticonvulsants. [Pg.195]

Figure 16.7 The structure of some established antiepileptic drugs (AEDs) and some newer ones. Note that while the structures of phenytoin and ethosuximide are similar and also close to that of phenobarbitone, they are effective in different forms of epilepsy. Vigabatrin, progabide and gabapentin are clearly related to GABA. Muscimol is a GABAa agonist but is not an effective antiepileptic drug...

Antiepileptics Phenytoin Carbamazepine Valproic acid Gabapentin Vigabatrin Ethosuximide Benzodiazepines... [Pg.19]

A 30-year-old female with partial seizures is treated with vigabatrin. What is the principal mechanism of action of vigabatrin ... [Pg.150]

The answer is d. (Katzung, pp 404-A05) Vigabatrin can induce psychosis. It is recommended that it not be used in patients with preexisting depression and psychosis. [Pg.166]

Anticonvulsants (barbiturates, including phenobar-bital and primidone carbamazepine felbamate phenytoin topiramate vigabatrin)... [Pg.350]

Similar addition reactions of alkyl 3-lithiopropiolates to nitrones with subsequent Raney Ni hydrogen reduction and amino group protection, led to the synthesis of (S) and (R)-vigabatrin (659). [Pg.280]

See also in sourсe #XX -- [ Pg.233 , Pg.339 , Pg.347 , Pg.406 ]

See also in sourсe #XX -- [ Pg.141 , Pg.157 ]

See also in sourсe #XX -- [ Pg.113 ]

See also in sourсe #XX -- [ Pg.135 ]

See also in sourсe #XX -- [ Pg.190 , Pg.191 ]

See also in sourсe #XX -- [ Pg.227 ]

See also in sourсe #XX -- [ Pg.347 , Pg.685 ]

See also in sourсe #XX -- [ Pg.477 ]

See also in sourсe #XX -- [ Pg.141 , Pg.157 ]

See also in sourсe #XX -- [ Pg.18 , Pg.102 , Pg.272 , Pg.422 ]

See also in sourсe #XX -- [ Pg.188 ]

See also in sourсe #XX -- [ Pg.110 ]

See also in sourсe #XX -- [ Pg.656 ]

See also in sourсe #XX -- [ Pg.35 , Pg.309 ]

See also in sourсe #XX -- [ Pg.92 ]

See also in sourсe #XX -- [ Pg.303 , Pg.312 , Pg.317 , Pg.318 ]

See also in sourсe #XX -- [ Pg.359 ]

See also in sourсe #XX -- [ Pg.86 ]

See also in sourсe #XX -- [ Pg.446 ]

See also in sourсe #XX -- [ Pg.190 ]

See also in sourсe #XX -- [ Pg.699 ]

See also in sourсe #XX -- [ Pg.733 , Pg.752 ]

See also in sourсe #XX -- [ Pg.35 , Pg.309 ]

See also in sourсe #XX -- [ Pg.718 , Pg.766 , Pg.767 , Pg.782 ]

See also in sourсe #XX -- [ Pg.421 ]

See also in sourсe #XX -- [ Pg.718 , Pg.766 , Pg.767 , Pg.782 ]

See also in sourсe #XX -- [ Pg.141 , Pg.157 ]

See also in sourсe #XX -- [ Pg.225 ]

See also in sourсe #XX -- [ Pg.217 ]

See also in sourсe #XX -- [ Pg.22 , Pg.508 ]

See also in sourсe #XX -- [ Pg.726 ]

See also in sourсe #XX -- [ Pg.508 ]

See also in sourсe #XX -- [ Pg.220 , Pg.222 , Pg.223 ]

See also in sourсe #XX -- [ Pg.248 ]

See also in sourсe #XX -- [ Pg.86 ]

See also in sourсe #XX -- [ Pg.485 ]

See also in sourсe #XX -- [ Pg.505 ]

See also in sourсe #XX -- [ Pg.248 ]

See also in sourсe #XX -- [ Pg.99 ]

See also in sourсe #XX -- [ Pg.4 ]

See also in sourсe #XX -- [ Pg.257 , Pg.258 ]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...