Venous thrombosis parenteral nutrition

Superior vena cava thrombosis has been described after frequent central venous catheterization and total parenteral nutrition, with eventual partial recovery (12). 

Muckart DJ, Neijenhuis PA, Madiba TE. Superior vena caval thrombosis comphcating central venous catheterisation and total parenteral nutrition. S Afr J Surg 1998 36(2) 48-51. 

Thrombosis can occur, especially (for unclear reasons) in patients suffering from AIDS. The incidence of symptomatic central venous thrombosis in patients with AIDS receiving home parenteral nutrition has been estimated at 0.009 per patient-month (80). However, in one... 

The advent of parenteral nutrition has opened new avenues for therapy and prevention of malnutrition in these children. However, the technique of parenteral nutrition in burns poses several special problems. Because of the nature of the burned wound, sepsis is a particular hazard. Placement of the catheter is difficult especially when the burns involve the upper trunk and the arms. Whirlpool debridement may compromise sterility at the site of the catheter entrance. On the other hand, infusion of calories through peripheral veins limits the caloric concentration of the infusate and require large volume to meet nutritional needs. There is also an increased incidence of venous thrombosis whenever the dextrose concentration of the infusate exceeds 10%. Some of these complications can partially be prevented by simultaneous infusion of fat emulsion which in addition to their high caloric content also appear to protect peripheral veins from thrombosis. The reported experience with parenteral nutrition in burned children is limited and critical reviews are nonexistent. We have therefore presented the experience with parenteral nutrition of both the Cincinnati and Boston Units of the Shriners Burns Institute. 

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