Vederas, John

John C. Vederas, University of Alberta, Edmonton, AB, Canada 2010 Elsevier Ltd. All rights reserved. 

We would like to acknowledge the work on posttranslational modification of proteins of those not cited in this chapter either due to the scope of the chapter or our ignorance. We thank Dr. Oleg V. Tsodikov for critical reading of the manuscript and help in the preparation of Figures 2, 6, and 9. SGT would also like to thank Professors John C. Vederas and Christopher T. Walsh for their invaluable support and mentorship. 

Carbon-carbon bond formation between sp -hybridized carbons is not easy even with organometallic reagents. John Vederas of the University of Alberta reports (Organic Lett. 5 2963, 2003) that UV irradiation at low temperature of diacyl peroxides such as 4 gives the coupled product 5. The diacyl peroxides can be prepared by the DCC-mediated condensation of acids with peracids,... 

Volume Editors Finian J. Leeper, John C. Vederas... 

Prof. John C. Vederas Department of Chemistry University of Alberta E3-44 Chemistry Building Edmonton T6G 2G2, Canada E-mail John. Vederas ualberta.ca... 

Finian J. Leeper, Cambridge John C.Vederas, Edmonton... 

Submitted by Sunil V. Pansare, Lee D. Arnold, and John C. Vederas/i Checked by P. S. Manchand, P. Mastrodonato-DeLora, and D. L. Coffen. 

Jonathan Kennedy, Karine Auclair, Steven G. Kendrew, Cheonseok Park, John C. Vederas and C. Richard Hutchinson, Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. Science, 284 (1999), 1368-1372. 

George Biichi (1921-1998) and John C. Vederas developed a synthesis, in which yS-ionone oxime is cyclised to an isoxazole under conditions similar to those for iodolactonisation Birch reduction of the isoxazole cleaves the N-O bond and produces a /3-aminoketone acid-catalysed elimination of ammonia then yields yS-damascone. [39]... 

Chris Diaper received his BSc in chemistry in 1996 from the University of Bradford, UK and his PhD in 2000 from the University of Sheffield under the supervision of Dr Alan Spivey. After postdoctoral work at the University of Nottingham with Prof Gerry Pattenden he moved to his current position as a postdoctoral fellow at the University of Alberta, Canada working with Prof John Vederas. His research interests include the development of germanium based linkers for solid-phase sjmthesis, the total synthesis of marine natural products and mechanistic aspects of the diaminopimelate (DAP) biosynthetic pathway. 

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