Vanadyl sulfate reduction

Vanadium(IV) Oxysulfate. Vanadium(IV) oxysulfate pentahydrate (vanadyl sulfate), VOSO4 -5H20) is an ethereal blue sohd and is readily soluble in water. It forms from the reduction of V20 by SO2 in sulfuric acid solution. Vanadium(III) sulfate [13701 -70-7] ) is a powerful... 

Elemental composition V 56.02%, O 43.98%. An acid solution is analyzed for vanadium (See Vanadium). Pentoxide in sulfuric acid may he converted to vanadyl sulfate hy reduction with SO2 (See Reactions) or ferrous ammonium sulfate (FAS). The excess FAS may he destroyed with ammonium persulfate. Vanadyl sulfate is then titrated with a standard solution of potassium permanganate ... 

Vanadium treatment in animals has been shown to interfere with the development of malignant tumors. In 1984, oral treatment with vanadyl sulfate was shown to decrease the induction of mammary carcinoma [167], New experiments have involved treatment to induce a mammary carcinoma in rats started on oral vanadate treatment that continued for 35 weeks. Vanadium treatment protected the rat from development of cancer as determined histologically. In addition, a significant reduction in incidence of total number of tumors and a delay in time to tumor appearance was observed. Vanadium-treated animals had lower tissue distribution of metallothio-nein, a prognostic marker for breast cancer. The mammary tissue in the vanadium-treated group showed increased apoptosis, which could be related to the anticarci-nogenic effect [168],... 

Ramasarma, T. and H.N. Ravishankar. 2005. Formation of an oxo-radical of perox-ovanadate during reduction of diperoxovanadate with vanadyl sulfate or ferrous sulfate. Biochim. Biophys. Acta 1722 30-35. 

Supported oxides and hydroxide nanoparticles have also been employed for selox [107, 117, 118). Zeolite-confined nano-Ru02 exhibits excellent activity and selectivity toward aldehydes and ketones without employing sacrificial reductants or cocatalysts [117]. Titania-supported nano-PdO is another promising candidate for benzyl alcohol selox, which demonstrates excellent activity [118]. Vanadyl sulfates have recentiy been shown as efficient catalysts for benzyl alcohol oxidation in the presence of trace water [119]. 

The X-ray microanalytical studies suggest that accumulated vanadium is not found in aqueous intracellular volumes such as vacuoles but occurs mainly in hydrophobic granules and membranes. Chelation by a mixture of ligands including water, sulfate, and tunichrome could have two effects on the lower oxidation states of vanadium, namely, to decrease the reduction potential and increase the stabilization at physiological pH. The EPR line-width studies (145), carried out on whole blood samples and based on aqua vanadyl models, may simply be inappropriate or applicable to only a fraction of the acciunulated vanadium. 

---