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Valproic acid 2156 Vitamin

Recently, Prasad et al. cloned a mammalian Na+-dependent multivitamin transporter (SMVT) from rat placenta [305], This transporter is very highly expressed in intestine and transports pantothenate, biotin, and lipoate [305, 306]. Additionally, it has been suggested that there are other specific transport systems for more water-soluble vitamins. Takanaga et al. [307] demonstrated that nicotinic acid is absorbed by two independent active transport mechanisms from small intestine one is a proton cotransporter and the other an anion antiporter. These nicotinic acid related transporters are capable of taking up monocarboxylic acid-like drugs such as valproic acid, salicylic acid, and penicillins [5], Also, more water-soluble transporters were discovered as Huang and Swann [308] reported the possible occurrence of high-affinity riboflavin transporter(s) on the microvillous membrane. [Pg.264]

Phenytoin, carbamazepine, phenobarbital, oxcarbazepine, and valproic acid may interfere with vitamin D metabolism, causing asymptomatic high-turnover bone disease with normal bone density or decreased bone mineral... [Pg.601]

Medical drugs Antibiotics (tetracyclines), anticancer drugs, anticonvulsants (valproic acid), lithium, retinoids (vitamin A), thalidomide, diethylstilbestrol (DES), anticoagulants (warfarin)... [Pg.219]

Valproic Acid Syrup Vitamin E Borosilicate glass, 2M X 4mm I.D. 2-5% liquid G2/S1AB 80-10 mesh) Nitrogen 245-265 EID Hexadecyl Hexadecanoate USP (24, pp. 1747 and 1749)... [Pg.482]

Clinically important, potentially hazardous interactions with acetaminophen, acitretin, aspirin, chloroquine, digoxin, doxepin, fat-soluble vitamins A, D, E, K, hydroxychloroquine, isotretinoin, lovastatin, mycophenolate, raloxifene, sulfasalazine, sulfonylureas, tetracycline, tricyclic antidepressants, ursodeoxycholic acid, valproic acid... [Pg.122]

A 47-year-old woman with multiple medical problems stabilised on warfarin (and also taking azathioprine, captopril, furosemide, insulin, capto-pril, prednisone, levothyroxine, valproic acid and zolpidem) had all her teeth removed under general anaesthetic. Sixteen days later she needed a dental abscess drained and was given oral clindamycin 300 mg four times daily with ibuprofen 600 mg for any discomfort. On day 17 she needed a suture to stop some bleeding and her INR was found to be 3.5. By day 20 she had developed more severe oral bleeding, which needed emergency room treatment. Her INR was found to have risen to 13 and her haemat-ocrit decreased to 18%. She was treated successfully with a blood transfusion and vitamin K. ... [Pg.368]

Elmazar, M.M., Thiel, R., and Nau, H., 1992. Effect of supplementation with folinic acid, vitamin B6, and vitamin B12 on valproic acid-induced teratogenesis in mice. Eundamentals of Applied Toxicology. 18 389-394. [Pg.553]


See other pages where Valproic acid 2156 Vitamin is mentioned: [Pg.602]    [Pg.244]    [Pg.596]    [Pg.608]    [Pg.985]    [Pg.1294]    [Pg.247]    [Pg.192]    [Pg.583]    [Pg.284]    [Pg.3006]    [Pg.494]    [Pg.496]    [Pg.499]    [Pg.500]    [Pg.1029]    [Pg.1436]    [Pg.1436]    [Pg.2567]    [Pg.616]    [Pg.577]   
See also in sourсe #XX -- [ Pg.12 , Pg.1028 ]




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