UV matrix-assisted laser desorption/ionization

Knochenmuss, R. (2002) A quantitative model of UV matrix-assisted laser desorption/ ionization. J. Mass Spectrom., 37, 867. 

Glocker, M.O. Bauer, S.H.J. Kast, J. Volz, J. Przybylski, M. Characterization of Specific Noncovalent Protein Complexes by UV Matrix-Assisted Laser Desorption Ionization Mass Spectrometry, J. Mass Spectrom. 31, 1221-1227 (1996). 

Bahr, U., Deppe, A., Karas, M., Hillenkamp, R, and Giessman, U., Mass Spectrometry of Synthetic Polymers by UV-Matrix-Assisted Laser Desorption/ Ionization, Anal. Ghent., 64, 2866,1992. 

NordhofF, E., Kirpekar, F., Karas, M., Cramer, R., Hahner, S., HiUenkamp, F., Kristiansen, K., RoepstorfF, P., and Lezius, A. (1994) Comparison of IR- and UV-matrix-assisted laser desorption/ ionization mass spectrometry of oligodeoxynucleotides. Nucleic Acids Res., 22 (13), 2460-2465. 

Bahr, LF., Deppe,A., Karas, M., Hillenkamp, E, Geissmann, U. (1992) Mass spectrometry of synthetic polymers by UV-matrix-assisted laser desorption/ionization. And. Chem., 64,2866-2869. 

Mass spectrometry of synthetic polymers by UV-matrix-assisted laser desorption/ionization. Anal. Chem., 64, 2866. 

Erra-Balsells, R. Nonami, H. UV-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of synthetic polymers... 

Nonami, H. Tanaka, K. Fukuyama, Y. Erea-Balsells, R. p-CarboUne alkaloids as matrices for UV-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in positive and negative ion modes. Analysis of proteins of high molecular mass, and of cyclic and acyclic oligosaccharides. Rapid Commun. Mass Spectrom. 1998, 12, 285—296. 

Nordhoff, E. Ingendoh, A. Cramer, R. Overberg, A. Stahl, B. Karas, M. Hillenkamp, F. Crain, P. F. Matrix-assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the UV and IR. Rapid Comm. Mass Spectrom. 1992, 6,771-776. 

Wingerath, T. et al. (1999). Analysis of cyclic and acyclic analogs of retinol, retinoic acid, and retinal by laser desorption ionization-, matrix-assisted laser desorption ionization-mass spectrometry, and UV/Vis. spectroscopy. Anal. Biochem. 272(2) 232-242. 

The most discriminating technique for proving the identity and purity of analyte peak of a chromatogram, especially for analyzing biological samples and natural products, is by using online LC-UV/MS or GC-MS/FTIR methods [15]. Alternatively, one could use a combination of TLC and MS, where direct determination on the TLC plates is made by matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) [16]. 

Matrix assisted laser desorption ionization time-of-flight (MALDI-TOE) mass spectrometry was carried out with a PerSeptive Biosystems Voyager-DE-RP MALDl-TOF mass spectrometer. A 337-nm UV nitrogen laser producing 3-ns pulses was used in the reflectron mode. The samples were prepared by mixing 10 pi of a 0.1 M HAc solution of the sample with 20 pi of a solution of 3 mg/1 a-cyano-4-hydroxy cinnamic acid in wafer. One pi of that solution was loaded on the gold-sample plate. 

Mark-Honwink eqnation Relates limiting viscosity number (LVN) to molecular weight LVN = KM . matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) MS in which the sample is placed in a matrix that contains a strong ultraviolet (LTV) absorber chosen to match the UV absorption of the laser, which allows the molecules to become volatilized with minimal fragmentation. 

Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometer with UV laser (i.e., 337-nm nitrogen laser), MALDI probe, and optional delayed extraction and postsource decay... 

Because of expected electrical, electrochemical, optical, chemo-sensor, and other properties of the ball-type Pcs, several metallo and metal-free ball-type Pcs with different linkers have been reported. Metallo and metal free ball-type Pcs containing four calyx[4]arene units as linkers have been synthesized, Fig. 1 [37], The structures of compounds 1-3 were confirmed by UV-vis, IR, 1II-NMR, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), and elemental analysis. Because of their unique structure and versatile complexation properties [38], calixarenes were found to be one type of interesting compounds to be incorporated into Pc. The cone conformation of the t-butylcalix[4]arene direct... 

Chen, X.J., Carroll, J.A. and Beavis, R.C. (1998) Near-UV-induced matrix-assisted laser desorption/ionization as a function of wavelength. /. Am. Soc. Mass Spectrom., 9 (9), 885-91. 

Elaboration of nerve agent toxicokinetics requires sophisticated analytical tools to detect and, if possible, to quantify the free toxicants as well as adducts with proteins and enzymes. Analysis of OP nerve agents has been performed by capillary electrophoresis (CE), biosensors, matrix-assisted laser desorption/ionization (MALDI) MS, desorption electrospray ionization MS (DESI MS), ion mobility time-of-flight MS (IM-TOF MS), nuclear magnetic resonance spectroscopy (NMR), LC-UV, gas chromatography (GC), and many more techniques (Hooijschuur et al, 2002 John et al, 2008). 

MALDI-MS refers to matrix-assisted laser desorption-ionization mass spectroscopy, It is also called MALFI-TOF, because the mass spectrometer is a time-of-flight version. In this technique, the polymer is mixed with a molar excess of a salt, for cationization, and deposited on a probe surface. A UV laser is pulsed... 

Figure 7-6 A generic view of the process of matrix-assisted laser desorption Ionization. Co-crystallized matrix and analyte molecules are irradiated with a UV laser.The laser vaporizes the matrix, producing a plume of matrix ions, analyte ions, and neutrals. Gas-phase ions are directed into a mass analyzer.

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