Uterine inflammation

While many females And this process relatively painless, painfrtl menstruation, or dysmenorrhea, can result from uterine inflammation and contraction or from severe medication conditions involving nearby pelvic organs or tissues. However, many females experience a combination of troublesome physical and psychological symptoms seven to ten days before the start of menses (called the luteal phase in the ovarian cycle and... 

Pelvic inflammatory disease (PID) Inflammation of the endometrium, uterine tubes, and pelvic peritoneum. PID is often due to a sexually transmitted infection. 

Leucorrhea. A whitish, viscid discharge from the vagina and uterine cavity. Leukocyte. White blood cells. Leukocytosis. A transient increase in the number of leukocytes in the blood, resulting from hemorrhage, fever, infection, inflammation, etc. 

Many small peptides exert their effects at very low concentrations. For example, a number of vertebrate hormones (Chapter 23) are small peptides. These include oxytocin (nine amino acid residues), which is secreted by the posterior pituitary and stimulates uterine contractions bradykinin (nine residues), which inhibits inflammation of tissues and thyrotropin-releasing factor (three residues), which is formed in the hypothalamus and stimulates the release of another hormone, thyrotropin, from the anterior pituitary gland. Some extremely toxic mushroom poisons, such as amanitin, are also small peptides, as are many antibiotics. 

In 1902, A Compend of Materia Medica, Therapeutics, and Prescription Writing prescribed Cannabis indica—Indian hemp for a variety of colorful conditions Uterine affections, as chronic metritis [inflammation of the womb], subinvolution, menorrhagia, dysmen-orrhoea [painful menstruation], etc.,—its powers as an anodyne and stimulant of the uterine muscular fibre render it a very efficient agent. ... 

Prostaglandins Lower blood pressure Inhibit blood platelet aggregation Control inflammation Lower gastric secretions Stimulate uterine contractions Relax smooth muscles of the uterus... 

In severe endometriosis, infertility likely results from distortion of the pelvic structure secondary to endometrial lesions, inflammation, and adhesions. In milder disease, the cause-effect relationship is more controversial. Decreased oocyte viability and/or production resulting from the altered uterine environment may be a contributing factor. ... 

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