Ursolic add

Fatty acids, n-hydroxy acids, ursolic add Apply sample solution, followed by methanolic boron trifluoride solution, heat with a hot-air drier, allow to cool and develop. 170]... 

Another approach to improved chemoselectivity utilizes sterically hindered alkenes, as reported by Konoike et al. (Scheme 3.25) [115]. Ursolic add 12, a steroid with a highly congested trisubstituted double bond, undergoes allylic hydroxylation at the C-ll position with MCPBA and tetrakis(pentafluorophenyl)porphyrin iron chloride [Fe(PFPP)Cl] as a catalyst to give a single diastereomer 13 in 91% yield. With sterically less encumbered systems only epoxidation was observed. 

Quercetin, isorhamnetin, quercitrin, kaempferol 3-O-rutinoside, isorhamnetin 3-O-glucoside, and morin Betulinic acid, oleanolic add, and ursolic add Vanillic acid, caffeic add, p-coumaric add, ferulic acid, delphinidin, cyanidin, quercetin, kaempferol, isorhamnetin, procyanidin B2, and procyanidin B3... 

Bheemasankara Rao C, Suseela K, Subba Rao PV, Gopala Krishna P, Subba Raju GV (1984) Chemical examination of some Indian medicinal plants. Indian 1 Chem 23B 787-788 Bianchi E, Girardi F, Diaz F, Sandoval R, Gonzales M (1963) Components of the leaves and fruit of Cestrum parqui Tigogenin, digalogenin, digitogenin, and ursolic add. 1. Ann Chim (Rome) 53 1761-1778... 

Mate folium Mate, Jesuit s tea ilex paruguariensis St.HIL. Aquifoliaceae DAC 86, MI) 0,3%-17% caffeine 0.03%-0.05% theophylline 0.2%-0.45% theobromine 10% chlorogenic-, iso- and neochlorogenic add, isoquercitrin Triterpene saponines ursolic and oleaiiolic acid derivatives Fig. 29,30... 

Chemical studies of numy other species of Randia have shown the presence of triterpenoid acids such as oleanolic add and randialic add. Previous work on the roots of R. siamensis yielded mesembryanthemoidigenic acid, 3-P-acetyloleanolic add, ursolic acid and 3-0-(a-L-arabinosyl)-oleanolic add (Lapikanom et al., 1983 Woo et al., 1984). However, there have been no previous reports of compounds isolated from the fhiit of this plant. 

Ursolic, oleanolic, and betuUnic adds as well as miscellaneous vegetable extracts were developed on RP C18 plates using n-hexane/ethyl acetate (5 1). A TLC-MS approach was employed to confirm the presence of the adds in the plant extracts studied. A CAMAG TLC-MS interface was used for the elution of compounds from TLC plates into the ion trap mass spectrometer with an APCI source. Mass spectra were recorded in negative-ion mode. In order to differentiate between the isomeric ursolic, oleanolic, and betulinic adds by means of MS, tand and triple MS experiments were performed. Betulinic add conld be readily distinguished from ursolic and oleanolic adds. MS/MS/MS spectra of the two latter adds varied mainly in the... 

TTie microbial transformation of ursolic acid (87) by, filamentous fungus Syncephalastrum racemosum CGMCC 3.2500 produced, in low 5aelds, five metabolites [87] 3p,7p,2ip-trihydroxy-m s-12-en-28-oic add (108), 3p,21p-dihydroxy-urs-ll-en-28-oic acid-13-lactone (111), ip,3p,2ip-trihydroxy-urs-12-en-28-oic acid (109), 3p,7p,2ip-tri-hydroxy-urs-l-en-28-oic acid-13-lactone (112), and 21-oxo-lp,3p-dihydroxy-urs-12-en-28-oic acid (110) (Figure 28.36). In addition, the anh-HCV achvity of compounds 108-112 was evaluated and shown to have no potential in Ihe treatment of HCV. 

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