Uronic acids, polysaccharides containing

Ion Exchange. Acidic polysaccharides containing uronic acids, sulfate, or phosphate groups are cation exchangers, binding metal ions. The... 

Immunopolysaccharides. Part I, Preliminary Studies of a Polysaccharide from Azotobacter chroococcum, containing a Uronic Acid, G. J. Lawson and M. Stacey, J. Chem. Soc., (1954) 1925-1931. 

The first paper on the bioactive polysaccharides from Glycyrrhiza uralensis roots was published in 1996 by Kiyohara et al. [57]. They isolated a pectic type polymer with anti-complementary and mitogenic activity that was an acidic pectin, possibly containing rhamnogalacturonan type I as part of the total structure. Degradation of the uronic acid part of the molecule decreased both types of bio activities. The neutral oligosaccharide chains were shown to retain some of the activities of the native polymer, but it was suggested that they should be attached to the acidic core to retain maximum activity. 

De Ruiter, G. A., Schols, H. A., Voragen, A. G. J., and Rombouts, F. M., Carbohydrate analysis of water-soluble uronic acid-containing polysaccharides with high-performance anion-exchange chromatography using methanolysis combined with TFA hydrolysis is superior to four other methods, Anal. Biochem., 207, 176, 1992. 

Although the glycosidic bonds of uronic acid residues are usually more resistant to acid hydrolysis than those of neutral polysaccharides,218 these linkages in heparin are more readily cleavable then those between the hexosamine and the uronic acid residues. Disaccharides obtained by exhaustive hydrolysis of heparin with 0.5 MHC1 at 80° contained hexu-... 

The purification of a pneumococcal polysaccharide may be difficult, and the polysaccharide material is sometimes contaminated by a cell-wall component known as the C-substance. The methods for structural analysis of polysaccharides (which, like several of the pneumococcal polysaccharides, contain amino sugar and uronic acid... 

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